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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 241-503-7 | CAS number: 17496-08-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Remarks:
- The given result is the average of 4 calculation methods: - NICEATM - ACD/LABS - ACD/LABS consensus - OPERA
- Justification for type of information:
- See attachments
Data source
Reference
- Reference Type:
- publication
- Title:
- Chemistry Dashboard: Propionic acid, ammonium salt
- Author:
- U.S Environment Protection Agency
- Year:
- 2 017
- Bibliographic source:
- Environmental Protection Agengy
Materials and methods
- Principles of method if other than guideline:
- Endpoint:
Physical Chemical Properties 1.6.Octanol-water partition coefficient (Kow)
Comment on endpoint:
The logarithm of the ratio of the concentrations of a solute between the two solvents: octanol and water. LogP value is a measure of molecular lipophilicity or hydrophobicity. Lipophilicity affects drug absorption, bioavailability, hydrophobic drug-receptor interactions, metabolism of molecules, toxicity as well as environmental fate of chemicals.
Endpoint units:
Unitless ratio of concentrations.
Dependent variable:
LogP
Experimental protocol:
P = Concentration in octanol phase / Concentration in aqueous phase. The experimental data were downloaded from the EPI Suite data webpage (http://esc.syrres.com/interkow/EpiSuiteData.htm).
These data are from PHYSPROP (The Physical Properties Database) which is a collection of a wide variety of sources built by Syracuse Research Corporation (SRC). Experimental protocols of the different parts of data can be traced back to the original referenced literature from the database.
Endpoint data quality and variability:
The original data collected from the PHYSPROP database (15809 chemicals) have undergone a series of processes to curate the chemical structures and remove duplicates, obvious outliers and erroneous entries. Only good quality data with high consistency (14544 chemicals) was used for the development of the QSAR model. Then, QSAR-ready structures were generated by standardizing all chemical structures and removing inorganic and
metallo-organic chemicals (14208 chemicals). - Type of method:
- calculation method (fragments)
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Ammonium propionate
- EC Number:
- 241-503-7
- EC Name:
- Ammonium propionate
- Cas Number:
- 17496-08-1
- Molecular formula:
- C3H6O2.H3N
- IUPAC Name:
- ammonium propionate
Constituent 1
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 0.251
- Temp.:
- 20 °C
- pH:
- > 8
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.