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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Acute toxicity to Daphnia Magna:
The acute toxicity of the test item to Daphnia magna was determined in a 48‑hour test according to the OECD Guideline for Testing of Chemicals, No. 202 (2004) and the Commission Regulation (EC) No. 440/2008, Part C.2. The test item is a sparingly soluble substance, which hydrolyses in aqueous solutions resulting in an organic degradation product and copper. Therefore, Water Accommodated Fractions (WAFs) with the loading rates of 0.10, 0.32, 1.0, 3.2 and 10 mg/L were tested to assess the toxicity of the test item to daphnids. The test was performed using glass tubes completely filled (without headspace) with test medium that were tightly sealed with glass stoppers to avoid possible losses of volatile components of the test item by evaporation (closed system).
A semi-static test design with a test medium renewal after 24 hours was used. For preparation of the WAFs, individual dispersions of the test item with the loading rates of 3.2 and 10 mg/L were prepared. The dispersions were intensively stirred for 3 hours to dissolve a maximum amount of the test item in the dispersions. After stirring, each of the dispersions was filtered through a membrane filter (0.45 µm).These resulting undiluted filtrates were tested as WAFs. The biological results are expressed based on loading rates, since the test item isa sparingly soluble compound, which hydrolyses immediately after being applied to aqueous solutions, forming an organic degradation product and copper.The EL50 (48h) on Daphnia Magna was found to be 0.61 mg/L based on loading rate.
Algal growth inhibition:
The impact of the test item on the growth of the freshwater green algal species Pseudokirchneriella subcapitata was investigated in a 72-hour static test according to the OECD Guideline 201 (2006, corrected 2011) and the Commission Regulation (EU) No 2016/266, C.3. The substance is a sparingly soluble substance, which hydrolyses in aqueous solutions resulting in an organic degradation product and copper. Therefore, Water Accommodated Fractions (WAFs) with the loading rates of 0.032, 0.10, 0.32, 1.0 and 3.2 mg/L were tested to assess the toxicity of the test item to algae. As a precaution, the test was performed using glass Erlenmeyer flasks completely filled (without headspace) with test medium that were tightly sealed with glass stoppers to avoid potential losses of test item by evaporation (closed system).
A static test was performed. For preparation of the WAFs a dispersion of the test item with the loading rate of 3.2 mg/L was prepared. The dispersion was intensively stirred for 3 hours at room temperature in the dark to dissolve a maximum amount of the test item in the dispersion. After stirring the dispersion was filtered through a pre-conditioned membrane filter (0.45 μm). The resulting undiluted filtrate was tested as a WAF. The preparation of the test media was based on the OECD Guidance Document No. 23 (Second Edition) on Aquatic Toxicity Testing of Difficult Substances and Mixtures, 2019.
The biological results are expressed based on loading rates, since the test item isa sparingly soluble compound, which hydrolyses immediately after being applied to aqueous solutions, forming an organic degradation product and copper.The EL10 (72h) on Green Algae was found to be 0.72 mg/L based on loading rate.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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