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EC number: 200-522-0 | CAS number: 61-90-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Surface tension
Administrative data
Link to relevant study record(s)
Description of key information
The surface tension of L-leucine was addressed in several publications available in the literature. These experiments showed that L-leucine behaves as a surface-active substance and the surface tension is ca. 71.6 mN/m at 20°C for an aqueous L-leucine solution at a concentration of 7.0 g/L.
Key value for chemical safety assessment
- Surface tension:
- 71.6
- in mN/m at 20°C and concentration in mg/L:
- 7 000
Additional information
There are 3 studies available that assess the surface tension of L-leucine in aqueous solutions. None of these studies was performed according to internationally accepted testing protocols or GLP, but the methods that were used were acceptable and the publications contain sufficient information to assess the quality of the experiments.
The outcome of the different studies are in good agreement with one another.
In a first publication the surface tension of aqueous solutions of L-leucine as function of temperature and concentration was measured using the drop volume method. L-leucine was found to behave as a surface-active substance. It forms a gaseous adsorbed film at the air/water surface at concentrations up to 0.059 mol/kg. At higher concentrations, an expanded state film is formed.
The surface tension was found to be ca. 71.6 at 20°C at an L-leucine concentration of 0.053 mol/kg in water (value deduced from graph).
In a second set of experiments, the surface tension of a solution of a 0.0497M solution of L-leucine in 0.10M aqueous NaCl was assessed using the differential capillary-rise method.
The surface tension of a 0.0497 molar solution of L-leucine in 0.10M aqueous NaCl was found to be ca. 70.1 mN/m.
Finally, in a third publication, the surface tension of L-leucine in aqueous solution was measured using the Wilhelmy plate method and was found to be ca. 67 mN/m for a 0.14M aqueous L-leucine solution (value deduced from graph).
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