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Diss Factsheets
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EC number: 205-406-3 | CAS number: 140-26-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Classification of Phenethyl isovalerate for effects in the environment
In determining the classification appropriate to Phenethyl isovalerate, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.
Persistence
Available data indicates that Phenethyl isovalerate is not persistent in the aquatic and soil environment. Moreover, its persistent characteristics is only observed in the sediment compartment but its diffusion in sediment is very less, to the level of 0.927%. Hence it has been concluded that Phenethyl isovalerate is not persistent in nature.
Thus, Phenethyl isovalerate is classified as a not persistent chemical.
Potential to accumulate
The estimated log Kow values for Phenethyl isovalerate is less than 4 (mean Log Kow = 3.883). The potential for Phenethyl isovalerate to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the reported BCF value for the substance is less than 2000.
The estimated BCF of Phenethyl isovalerate is highest 193.9 L/kg wet wt. and below the threshold of 2000.
Thus, Phenethyl isovalerate does not satisfy the criterion for classification as bioaccumulative (B).
Toxicity
The toxicity values of invertebrates and algae are reported as EC50 = 1.956 mg/L and EC50 = 3.094 mg/L, respectively. These values suggest classification for aquatic toxicity in the Aquatic Chronic 2 category. But the BCF value of Phenethyl isovalerate reported was not >= 500.(Does not fullfill CLP criteria for toxic classification).Thus considering the CLP Criteria for aquatic classification of the substance , it is concluded that Phenethyl isovalerate is non hazardous to the aquatic environment.
In addition to aquatic toxicity, the substance, Phenethyl isovalerate, is not classified as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) according to CLP (Regulation (EC) No 1272/2008) and there is no evidence of chronic toxicity, as identified by the classifications STOT (repeated exposure) according to Regulation (EC) No 1272/2008.
Thus, Phenethyl isovalerate does not meet the criterion for classification as toxic (T).
Thus, in accordance with the requirements of Annex XIII; it can be inferred that Phenethyl isovalerate is a not a PBT (including vPvB) substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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