Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 240-212-2 | CAS number: 16068-37-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://chesar.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Endpoint summary
Administrative data
Description of key information
4,4,7,7-Tetraethoxy-3,8-dioxa-4,7-disiladecane is a liquid at standard temperature and pressure, with a measured melting point of -34°C and a measured boiling point of 267.7°C. It has a measured relative density of 0.966 at 20°C and a measured vapour pressure values of 0.3 Pa at 20°C and 6.3 Pa at 50°C.
The substance is not classified as a flammable liquid according to Regulation (EC) No. 1272/2008 on the basis of a measured flash point of 116.5°C and a measured boiling point of 267.7°C. It has a measured auto-ignition temperature of 228°C at 969 -979 hPa and is not explosive and not oxidising on the basis of structural examination.
In contact with water, 4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane reacts moderately (half-life of 36 hours at pH 7, 0.8 hours at pH 4, 0.7 hours at pH 5 and 0.5 hours at pH 9 and 20-25°C) to produce 1,1,1,4,4,4-hexahydroxy-1,4-silabutane and ethanol according to the following equation:
C14H34O6Si2+ 6H2O → C2H10O6Si2 + 6C2H6O
The key physicochemical properties of the parent submission substance have been predicted using a validated QSAR estimation method. 4,4,7,7 -Tetraethoxy-3,8-dioxa-4,7-disiladecane has a predicted log Kow value of 2.7 at 20°C and predicted water solubility value of 20 mg/L at 20°C.
The saturation concentration in water of the silanol hydrolysis product, 1,1,1,4,4,4-hexahydroxy-1,4-silabutane, is limited by condensation reactions to approximately 100-500 mg/l. However, it is very hydrophilic (calculated solubility is 1E+06 mg/l at 20°C using a QSAR method), has a predicted log Kow value of -4.0 and it has a predicted vapour pressure of 4.4E-0.8 Pa at 25°C.
Ethanol has a reported log Kow of -0.3, vapour pressure of 7910 Pa at 25°C and is miscible with water.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)