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EC number: 206-585-0 | CAS number: 355-42-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Reference substance name:
- Tetradecafluorohexane
- EC Number:
- 206-585-0
- EC Name:
- Tetradecafluorohexane
- Cas Number:
- 355-42-0
- Molecular formula:
- C6F14
- IUPAC Name:
- tetradecafluorohexane
- Test material form:
- liquid
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- <= 0.1 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Temp.:
- 20 °C
- pH:
- >= 7.1 - <= 7.2
- Details on results:
- 9.3. Results
9.3.1. Preliminary Test
After 1 day of stirring, a gas bubble was observed in all three vials. At the end of the 47-hour stirring period, one vial was opened and analysed diluted and undiluted. The maximum content of test item dissolved was < 0.4 mg/L.
9.3.2. Main Study
After 1 day of stirring, a gas bubble was observed in all of the three vials. The results for the samples taken at 24, 48 and 72 hours are given in Table 4.
Analysis of triplicate samples from the same vial, showed good repeatability of the analytical method indicating that no undissolved test item was present in the samples. The results of the water solubility after stirring for 24, 48 and 72 hour test samples however show a much larger spread due to the nature of the test item. It is not possible to obtain an accurate value water solubility. Based on the results, water solubility of the test item is reported to be ≤ 0.1 mg/L.
A small response at the retention time of the test item was detected in the chromatograms of the pretreated sample from the blank water mixture. It was considered to derive from carry- over in the analytical system since similar responses were found in the analytical blanks. The calculated amount of 0.073 ng/mL (calculated by extrapolation of the calibration curve) was considered to have no significant effect on the results of the test samples.
Any other information on results incl. tables
Table 4
Main study - water solubility of the test item
Stirring time [hours] |
Analyzed concentration [ng/mL] |
pH |
24 |
117 |
7.1 |
|
125 |
|
|
116 |
|
48 |
1.01 |
7.2 |
|
1.01 |
|
|
1.01 |
|
72 |
20.1 |
7.2 |
|
20.5 |
|
|
20.5 |
|
1 Estimated value, calculated by extrapolation of the calibration curve.
Applicant's summary and conclusion
- Conclusions:
- The slow-stirring flask method was applied for the determination of the water solubility of Tétradécafluorohexane.
The water solubility of the test item at 20°C was ≤0.1 mg/L. The pH of the aqueous samples was 7.1 and 7.2.
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