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EC number: 428-710-1 | CAS number: 207574-76-3
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: "Particle Size Distribution, Fibre Length and Diameter Distribution" Guidance document, European Commission, ECB/TM/Feb 1996
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Key result
- Percentile:
- D10
- Mean:
- ca. 7.82 µm
- St. dev.:
- 0.157
- Key result
- Percentile:
- D50
- Mean:
- ca. 33.23 µm
- St. dev.:
- 0.395
- Key result
- Percentile:
- D90
- Mean:
- ca. 66.82 µm
- St. dev.:
- 1.178
- Conclusions:
- With a median mass diameter of about 33.23 µm, more than 98% of the particles were smaller than 100µm.
- Executive summary:
The particle size distribution of the test item was performed according to the EC Guidance Document ECB/TM/February 1996 "Particle Size Distribution, Fibre Length and Diameter Distribution" using laser diffraction.
Water was used as solvent. Two solutions were prepared, both measured in duplicate.
With a median mass diameter of about 33.23 µm, more than 98% of the particles were smaller than 100µm.
Reference
Description of key information
D10: ca. 7.82 µm
D50: ca. 33.23 µm
D90: ca. 66.82 µm
Test item is produced and used in its dissolved form: there is no chance of inhalative exposure during entiry life cycle
Additional information
With a median mass diameter of about 33.23 µm, more than 98% of the particles were smaller than 100µm.
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