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EC number: 225-555-8 | CAS number: 4926-55-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 of the 2-[(2-nitrophenyl)amino]ethanol on Daphnia magna after 48 h of exposure under static conditions is 92.8 mg/L (95% confidence Interval = 70.9 - >100 mg/L) expressed as nominal concentration (measured concentrations represent more than 80% of the nominal concentrations). The 48h-EC10 is 46.7 mg/L (95% confidence Interval : 32.9 - 66.3 mg/L) and the NOEC is 20.7 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 92.8 mg/L
Additional information
The acute toxicity of the substance 2-[(2-nitrophenyl)amino]ethanol to Daphnia magna was tested according to the OECD guideline 202 and the EU method C.2, and in conformity with the GLP.
The study was conducted under static conditions. 20 daphnies were exposed during the 48h to the following nominal concentrations : 4.3 - 9.4 - 20.7 - 45.5 - 100 mg/L. Analysis by High Performance Liquid Chromatography of the tested concentrations at the start of the test and after 48 of exposure demonstrate that the measured concentrations represents more than 80% of the nominal concentrations. So the results are expressed as nominal concentrations.
The water quality parameter (pH, oxygen) measured at T0 and T48h were within the acceptable limits. No immobilisation was observed in the controls. The validity criteria of the guideline were fulfilled.
The EC50 of teh substance 2 -[(2 -nitrophenyl)amino]ethanol on Daphnia magna after 48 h of exposure is 92.8 mg/L (95% confidence interval = 70.9 - >100mg/L) expressed as nominal concentration (measured concentration more than 80% of the nominal concentration). The 48h-EC10 is 46.7 mg/L (95% confidence interval : 32.9 - 66.3 mg/L) and the NOEC is 20.7 mg/L.
This study is classified as acceptable and satisfies the guideline requirement.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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