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EC number: 619-057-3 | CAS number: 94667-33-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988-06-21 - 1989-12-29
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Remarks:
- Study was conducted in accordance with the guidelines (U.S. EPA-FIFRA N-163-1 40 CFR, sec. 158.130 and 158.50), compliant with GLP and no deviations.
- Qualifier:
- according to guideline
- Guideline:
- other: U.S. EPA-FIFRA Guideline N-163-1
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: 40 CFR, Sec. 158.130 and 158.50
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable.
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
- Radiolabelling:
- yes
- Test temperature:
- 25 ºC +/-1ºC
- Details on study design: HPLC method:
- No information provided.
- Analytical monitoring:
- not specified
- Details on sampling:
Adsorption: One-gram samples of each soil were placed into sterile, tared nalgene bottles. Triplicate aliquots (200 ml) of each standard solution were added to bottles to achieve nominal concentrations of 0.0, 0.70, 3.50, 5.25 and 7.00 µg/ml. Soil suspensions were shaken in a dark environmentally controlled chamber at 25+/-1 ºC for 24 hours. Suspensions were then centrifuged (2000 rpm/15 minutes) and supernatants and soil were separated. Before removing the supernatant, the equilibrium pH was measured using a suitable pH meter.
Desorption: Appropriate aliquots of fresh 0.01M CaCl2 solution were added to each sample according to the volume removed after the adsorption phase. The soil suspensions were shaken for 24 hours in a dark environmentally controlled chamber at 25+/-1 ºC. Suspensions were then centrifuged (2000 rpm/15 minutes) and supernatants and soil were separated. The 7.00 µg/ml samples were subject to two further desorption cycles.- Details on matrix:
- Soil types used were sand, sandy loam, silty clay loam, and silt loam. The soil:water ratio was 1:200 soil:water.
Soil #92 Sand, Northwood, ND
% Organic matter = 0.5
% Sand = 92
% Silt = 4
% Clay = 4
Cation exchange capacity meq/100g = 0.3
pH = 7.4
Field capacity at 1/3 Bar Percent = 1.87
Bulk density gm/cm3 = 1.64
Soil #93 Sandy Loam, Northwood, ND
% Organic matter = 1.8
% Sand = 78
% Silt = 10
% Clay = 12
Cation exchange capacity meq/100g = 0.7
pH = 6.3
Field capacity at 1/3 Bar Percent = 14.41
Bulk density gm/cm3 = 1.23
Soil #91 Silty Clay Loam, Northwood, ND
% Organic matter = 4.1
% Sand = 16
% Silt = 52
% Clay = 32
Cation exchange capacity meq/100g = 32.3
pH = 7.9
Field capacity at 1/3 Bar Percent = 35.92
Bulk density gm/cm3 = 1.10
Soil #90 Silt Loam, Northwood, ND
% Organic matter = 4.2
% Sand = 24
% Silt = 52
% Clay = 24
Cation exchange capacity meq/100g = 22.7
pH = 7.4
Field capacity at 1/3 Bar Percent = 35.92
Bulk density gm/cm3 = 1.08 - Details on test conditions:
- The conditions for the definitive test were selected based on the results from two preliminary tests. From these tests, the test material was shown to be stable in the soil/solution mixture for at least 24 hours. The desired 20-80% adsorbed range could not be obtained with the preliminary 1:10 or 1:50 soil to solution ratio, a ratio of 1:200 (soil to solution) was selected for the definitive study. Results from a nalgene adsorption test demonstrated that DDAC did not adsorb to the nalgene test containers.
Nominal concentrations: 0.0, 0.70, 3.50, 5.25, 7.00 µg/ml
Measured concentrations (LSC analysis): 0.0, 0.665, 3.69, 5.36, 7.40 µg/ml
The definitive soil adsorption/desorption study was conducted at 25+/-1ºC in the dark with DDAC and four soils (1 x sand, 1 x sandy loam, 1 x silty clay loam and 1 x silt loam).
The definitive study was conducted at a 1:200 soil to water ratio, and an equilibrium time of 24 hours was used.
For adsorption, one-gram samples of soil were placed into sterile Nalgene bottles; triplicate aliquots of each standard solution were added to the Nalgene bottles. Soil suspensions were shaken in dark environmental chamber at 25 ºC for 24 hours.
For desorption, soil samples from the adsorption phase were shaken with 0.01 m CaCl2 for 24 hours in dark environmental chamber at 25 ºC. Suspensions were then centrifuged and supernatants and soil were separated. - Sample No.:
- #1
- Duration:
- 24 h
- Initial conc. measured:
- >= 0.7 - <= 7 mg/kg soil d.w.
- Temp.:
- 25 °C
- Sample No.:
- #2
- Duration:
- 24 h
- Initial conc. measured:
- >= 0.7 - <= 7 mg/kg soil d.w.
- Temp.:
- 25 °C
- Sample No.:
- #3
- Duration:
- 24 h
- Initial conc. measured:
- >= 0.7 - <= 7 mg/kg soil d.w.
- Temp.:
- 25 °C
- Sample No.:
- #4
- Duration:
- 24 h
- Initial conc. measured:
- >= 0.7 - <= 7 mg/kg soil d.w.
- Temp.:
- 25 °C
- Sample no.:
- #1
- Duration:
- 24 h
- Sample no.:
- #2
- Duration:
- 24 h
- Sample no.:
- #3
- Duration:
- 24 h
- Sample no.:
- #4
- Duration:
- 24 h
- Computational methods:
- No information provided.
- Key result
- Sample No.:
- #1
- Type:
- Koc
- Value:
- 437 805 dimensionless
- Temp.:
- 25 °C
- Matrix:
- sand
- % Org. carbon:
- 0.25
- Remarks on result:
- other: sample #92
- Sample No.:
- #2
- Type:
- Koc
- Value:
- 908 757 dimensionless
- Temp.:
- 25 °C
- Matrix:
- Sandy loam
- % Org. carbon:
- 0.9
- Remarks on result:
- other: sample #93
- Sample No.:
- #3
- Type:
- Koc
- Value:
- 1 599 564 dimensionless
- Temp.:
- 25 °C
- Matrix:
- Silty clay loam
- % Org. carbon:
- 2.05
- Remarks on result:
- other: sample #91
- Sample No.:
- #4
- Type:
- Koc
- Value:
- 1 469 081 dimensionless
- Temp.:
- 25 °C
- Matrix:
- Silt loam
- % Org. carbon:
- 2.1
- Remarks on result:
- other: sample #90
- Phase system:
- other: Koc
- Type:
- other: Koc
- Value:
- 1 599 564
- Remarks on result:
- other: Adsorption phase in #91 silty clay loam
- Phase system:
- other: Koc
- Type:
- other: Koc
- Value:
- 1 469 081
- Remarks on result:
- other: Adsorption phase in #90 silt loam
- Phase system:
- other: Koc
- Type:
- other: Koc
- Value:
- 236 473
- Remarks on result:
- other: Mobility coefficient desorption phase in #92 sand
- Phase system:
- other: Koc
- Type:
- other: Koc
- Value:
- 230 498
- Remarks on result:
- other: Mobility coefficient desorption phase in #93 sandy loam
- Phase system:
- other: Koc
- Type:
- other: Koc
- Value:
- 405 328
- Remarks on result:
- other: Mobility coefficient desorption phase in #91 silty clay loam
- Phase system:
- other: Koc
- Type:
- other: Koc
- Value:
- 367 334
- Remarks on result:
- other: Mobility coefficient desorption phase in #90 silt loam
- Details on results (HPLC method):
- No information provided.
- Adsorption and desorption constants:
- No information provided.
- Recovery of test material:
- Mass balance of DDAC (% of total) ranged from 80.81 to 117.99%
- Concentration of test substance at end of adsorption equilibration period:
- Soil Type Mean Mean Mean
Percent Adsorbed Percent Desorbed Mass Balance
#92 Sand 96.0 18.2 101%
#93 Sandy Loam 96.2 2.93 106%
#91 Silty Clay Loam 99.2 1.90 92.6%
#90 Silt Loam 99.0 1.34 105% - Concentration of test substance at end of desorption equilibration period:
- Refer to section 'Concentration of test substance at end of adsorption equilibrium period' above.
- Sample no.:
- #1
- Duration:
- 24 h
- % Adsorption:
- >= 80.45 - <= 92.86
- Sample no.:
- #2
- Duration:
- 24 h
- % Adsorption:
- >= 94.35 - <= 98.42
- Sample no.:
- #3
- Duration:
- 24 h
- % Adsorption:
- >= 99.09 - <= 99.71
- Sample no.:
- #4
- Duration:
- 24 h
- % Adsorption:
- >= 99.22 - <= 99.39
- Sample no.:
- #1
- Duration:
- 24 h
- % Desorption:
- >= 16.26 - <= 39.33
- Sample no.:
- #2
- Duration:
- 24 h
- % Desorption:
- >= 2.2 - <= 12.6
- Sample no.:
- #3
- Duration:
- 24 h
- % Desorption:
- >= 0.2 - <= 1.4
- Sample no.:
- #4
- Duration:
- 24 h
- % Desorption:
- >= 0.2 - <= 1.66
- Transformation products:
- not specified
- Details on results (Batch equilibrium method):
- No information provided.
- Statistics:
- No information provided.
- Validity criteria fulfilled:
- yes
- Conclusions:
- Didecyldimethylammonium Chloride has little or no potential for mobility in soil and should not pose an environmental risk for contamination of groundwater, under the conditions of this study.
- Executive summary:
In a study conducted in accordance with U.S.EPA-FIFRA Guideline N-163-1, aqueous14C-Didecyldimethylammonium Chloride (DDAC) was equilibrated with four soil types (sand, sandy loam, silty clay loam and silt loam) and adsorption and desorption coefficients and constants were determined. Initial test concentrations of the compound were 0.0, 0.70, 3.50, 5.35, 7.00 µg/ml. One-gram samples of soil were placed into sterile Nalgene bottles; triplicate aliquots of each standard solution were added to the Nalgene bottles. Soil suspensions were shaken in dark environmental chamber at 25 ºC for 24 hours. Suspensions were then centrifuged and supernatants and soil were separated. Soil samples from the adsorption phase were shaken with 0.01 m CaCl2for 24 hours in dark environmental chamber at 25 ºC. Suspensions were then centrifuged and supernatants and soil were separated. Sand samples were extracted with DMF-acetic acid for radioanalysis; all other soil types were combusted for radioanalysis. Sand had the lowest adsorption and desorption coefficients and adsorption phase mobility coefficient. loam had the lowest desorption phase mobility coefficient. Silty clay loam had the highest coefficients.Didecyldimethylammonium Chloride has little or no potential for mobility in soil and should not pose an environmental risk for contamination of groundwater, under the conditions of this study.
Reference
Sand had the lowest adsorption and desorption coefficients and adsorption phase mobility coefficient. loam had the lowest desorption phase mobility coefficient. Silty clay loam had the highest coefficients.
Adsorption and desorption coefficients.
Soil type |
Adsorption coefficient (Kd) |
Desorption coefficient (Kd) |
Mobility coefficient (adsorption phase) (Koc) |
Mobillity coefficient (desorption phase) (Koc) |
Sand |
1,095 |
591 |
437,805 |
236,473 |
Sandyloam |
8,179 |
2,074 |
908,757 |
230,498 |
Silty clay loam |
32,791 |
8,309 |
1,599,564 |
405,328 |
Silt loam |
30,851 |
7,714 |
1,469,081 |
367,334 |
Due to the immobility of DDAC, the percent adsorbed was not in the range 20 -80% which the Freundlich model typically describes the sorption characteristics of a compound. However, isotherms were determined with the correlation coefficents ranging from 0.9265 to 0.9970 for adsorption which implies that the data adequately fits the Freundlich model. Correlation coefficients for the desorption isotherms ranged from 0.8515 to 0.9361, therefore the isotherm determined, the Freundlich constants Kd and n, and the adsorption constants Koc based on the organic carbon content obtained from these were reported.
Description of key information
One key study is available, conducted in accordance with U.S.EPA-FIFRA Guideline N-163-1, with aqueous 14C-Didecyldimethylammonium Chloride (DDAC) as the test substance.
Key value for chemical safety assessment
Additional information
Key study:
In a study conducted in accordance with U.S.EPA-FIFRA Guideline N-163-1, aqueous 14C-Didecyldimethylammonium Chloride (DDAC) was equilibrated with four soil types (sand, sandy loam, silty clay loam and silt loam) and adsorption and desorption coefficients and constants were determined. Initial test concentrations of the compound were 0.0, 0.70, 3.50, 5.35, 7.00 µg/ml. One-gram samples of soil were placed into sterile Nalgene bottles; triplicate aliquots of each standard solution were added to the Nalgene bottles. Soil suspensions were shaken in dark environmental chamber at 25ºC for 24 hours. Suspensions were then centrifuged and supernatants and soil were separated. Soil samples from the adsorption phase were shaken with 0.01 m CaCl2 for 24 hours in dark environmental chamber at 25ºC. Suspensions were then centrifuged and supernatants and soil were separated. Sand samples were extracted with DMF-acetic acid for radioanalysis; all other soil types were combusted for radioanalysis. Sand had the lowest adsorption and desorption coefficients and adsorption phase mobility coefficient. loam had the lowest desorption phase mobility coefficient. Silty clay loam had the highest coefficients.Didecyldimethylammonium Chloride has little or no potential for mobility in soil and should not pose an environmental risk for contamination of groundwater, under the conditions of this study.
Overall Summary:
A study to determine adsorption and desorption in soil for N,N-Didecyl-N-methyl-poly(oxyethyl)ammonium Propionate was not carried out as an adequate study has been conducted on the chemical and structural analog, Didecyldimethylammonium Chloride. In view of the chemical and structural similarities, it is considered that the available data is adequate for N,N-Didecyl-N-methyl-poly(oxyethyl)ammonium Propionate.
Didecyldimethylammonium Chloride was classified as immobile in four soil/sediment types with the adsorption (Kd) and mobility (Koc) coefficients of Kd=1,095 and Koc=437,805 for sand, Kd=8,179 and Koc=908,757 for sandy loam, Kd=32,791 and Koc=1,599,564 for clay loam, and Kd=30,851 and Koc=1,469,081 for silt loam (Ref No 1792).
The results of the adsorption in soil study on a structural analog Didecyldimethylammonium chloride indicate little or no potential for mobility in soil and should not pose an environmental risk for contamination of ground water. Thus, it is considered that a short or a long-term Mobility- Lysimeter study is not justified.
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