Registration Dossier
Registration Dossier
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EC number: 237-748-4 | CAS number: 13967-50-5
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP complaint, guideline study, available as unpublished report acceptable without restrictions.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- Principles of method if other than guideline:
- The method used is based on a procedure designed to comply with that given in 'Particle size distribution, fibre length and diameter distribution', June 1996 European Commission technical guidance document, which satisfies the requirements of OECD Guideline 110.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- sieving
- No.:
- #1
- Size:
- < 100 µm
- Distribution:
- 17.6 %
- Remarks on result:
- other:
- Remarks:
- the proportion of potassium dicyanoaurate < 100 μm was 17.6%.
- Conclusions:
- In an OECD Granulometry screening test the proportion of potassium dicyanoaurate < 100 μm was 17.6%.
- Executive summary:
This is a GLP compliant, guideline study considered suitable for use as the key study for this endpoint. the proportion of potassium dicyanoaurate < 100 μm was 17.6%
Reference
The results of the sieving procedure are shown below:
Measurement |
Result |
Mass of test item transferred to sieve |
10.24g |
Mass of test item passed through sieve |
1.80g |
Proportion of test item <100µm |
17.6% |
Description of key information
The proportion of potassium dicyanoaurate < 100 μm was 17.6%.
Additional information
A GLP-compliant, guideline study is available for this endpoint (Harlan Laboratories 2011) and is considered suitable for use as the key study.
The dustiness of kaliumgoldcyanid was tested in a modified Heubach procedure according to standard guideline (Selck and Parr 2012). atmosphere. The total dustiness of kaliumgoldcyanid was determined to be 358.82 mg/g (35.9%). The inhalable fraction was 210.76 mg/g (47.2%), the thoracic fraction was 18.54 mg/g (0.09%) and the respirable fraction was 0.86 mg/g (0.03%). The Mass Median Aerodynamic Diameter (MMAD) was determined to be 29.0 μm with a geometric standard deviation of 1.7 μm.
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