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Diss Factsheets
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EC number: 617-441-5 | CAS number: 83121-18-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Hydrolysis:
In the key study (BASF DocID: TZ-322-001, 1987) teflubenzuron was found to be stable to hydrolysis at pH 5 and 7 after 30 d at 25°C. At a temperature of 25 °C and a pH of 9 the hydrolsis DT50 of teflubenzuron is 8.7 days . The hydrolysis DT50 of teflubenzuron at pH 9 was calculated to be 24.6 days at 12 °C (Chapter R.7b, p.222: Endpoint specific guidance Version 4.0 – June 2017). The metabolites identified after 30 days at pH 9 were 3,5-dichloro-2,4-difluorophenylurea (61% AR from the aniline label), 3,5-dichloro-2,4-difluoroaniline (12% AR from the aniline label), 2,6-difluorobenzoic acid (62% AR from the benzoyl label), 2,6-difluorobenzamide (12% AR from the benzoyl label), and N-(2,4-difluoro-3,5-dichlorobenzene)-5-fluoro[3H]-dihydroquinazoline-2,4-dione (8% AR from the aniline label and 5% AR from the benzoyl label).
Phototransformation in air:
Following the Atkinson calculation, the photochemical half-life for reactions with OH-radicals (12-hr day; 1.5 x 106 OH/cm3) was determined to be 1.7 days (BASF DocID: TZ-630-013).
Phototransformation in water:
Teflubenzuron was stable to photolysis for up to 7 days (93% AR as teflubenzuron, BASF DocID: TZ-322-002, 1987) at pH 5 and 25 °C. The degradation was then accelerated with 45% AR as teflubenzuron after 15 days. A photolytic half-life was estimated at about 10 days.
Since teflubenzuron was stable for up to 7 days, it was proposed that no aqueous photolysis studies are required on metabolites.
Phototransformation in soil:
In the study of Hawkins (1987, DocID: TZ-620-007) Teflubenzuron was photodegraded with a half-life of about 104 days. The metabolite 3,5-dichloro-2,4-difluorophenylurea appeared after 15 days at a level of 2% AR.
Photodegradation will not be the main degradation route of teflubenzuron in soil.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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