Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011-02-08 to 2011-02-11
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 2.78 - 5.64
- Temp.:
- 25 °C
- pH:
- 2.47
- Details on results:
- In the course of this study the partition coefficient (Pow) of Reaction product of 2-hydroxybenzoic acid, styrene and oxozinc was determined using high performance liquid chromatography (HPLC). The partition coefficient is given as a range, the determined log Pow 2.78 +/- 0.00 to 5.64 +/- 0.01 (95% confidence interval).
- Conclusions:
- In the course of this study the partition coefficient (Pow) of Reaction product of 2-hydroxybenzoic acid, styrene and oxozinc was determined using high performance liquid chromatography (HPLC). The partition coefficient is given as a range, the determined log Pow 2.78 +/- 0.00 to 5.64 +/- 0.01 (95% confidence interval)
The estimated Pow: 597 +/- 4 to 439761 +/- 10796 (95% confidence interval) - Executive summary:
The partition coefficient Pow was determined using high performance liquid chromatography based on a calibration curve with eight reference items. The capacity factors k were calculated from the dead time and retention times of the reference substances. As the test substance is a mixture (UVCB substance), the partition coefficient (Pow) of Reaction product of 2-hydroxybenzoic acid, styrene and oxozinc is given as a range. The log Pow was determined to lie between 2.78 +/- 0.00 and 5.64 +/- 0.01 (95% confidence interval).
Reference
Description of key information
In the course of this study the partition coefficient (Pow) of Reaction product of 2-hydroxybenzoic acid, styrene and oxozinc was determined using high performance liquid chromatography (HPLC). The partition coefficient is given as a range, the determined log Pow 2.78 +/- 0.00 to 5.64 +/- 0.01 (95% confidence interval)
The estimated Pow: 597 +/- 4 to 439761 +/- 10796 (95% confidence interval)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.21
- at the temperature of:
- 25 °C
Additional information
The key value of Log Kow was calculated by the mean of measured value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
