Registration Dossier
Registration Dossier
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EC number: 201-476-4 | CAS number: 83-43-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Guinea pig maximisation test was conducted in male Hartley guinea pigs.
- GLP compliance:
- not specified
- Type of study:
- guinea pig maximisation test
- Justification for non-LLNA method:
- None stated
- Species:
- guinea pig
- Strain:
- Hartley
- Sex:
- male
- Key result
- Remarks on result:
- no indication of skin sensitisation
- Interpretation of results:
- not sensitising
- Conclusions:
- The test substance showed no evidence of skin sensitization in male Hartley guinea pigs.
Reference
No evidence of skin sensitisation.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The test substance showed no evidence of skin sensitisation in male Hartley guinea pigs.
Justification for classification or non-classification
Skin sensitisation: Animal study give negative result
Therefore in accordance with Regulation (EC) No. 1272/2008 (as amended by Regulation (EC) No. 286/2011) Table 3.4.2, this substance should not be classified as skin sensitiser.
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