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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2012
Bibliographic source:
Ecosar v1.00 (Episuite v4.0), US EPA

Materials and methods

Test guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzene-1,2,4,5-tetracarboxylic acid
EC Number:
201-879-5
EC Name:
Benzene-1,2,4,5-tetracarboxylic acid
Cas Number:
89-05-4
Molecular formula:
C10H6O8
IUPAC Name:
benzene-1,2,4,5-tetracarboxylic acid

Study design

Test type:
not specified
Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
8.1 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

Executive summary:
With an EC50 growth rate of 8.1 mg/l in this 96h Algae study pyromellitic acid (PAM or benzene-1,2,4,5 -tetracarboxylic acid) would qualify as toxic to the aquatic environment, chronic category 2. However, this substance is also readily biodegradable. Therefore no classification is needed