Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 222-883-3 | CAS number: 3648-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 > water solubility, NOEC 0.0097 mg/L, OECD 201, Rufli (1988).
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 0.001 mg/L
Additional information
Since no data are available on the substance itself information has been read across to a product of its hydrolysis, dioctyltin oxide, and structural analogues of another hydrolysis product, lauric acid. The read across substance to lauric acid are sodium laurate and decanoic acid.
The toxicity of the test material to aquatic plants (Rufi, 1988b) was determined in a study conducted to standardised guidelines using the algal species Desmodesmus subspicatus (reported as Scenedesmus subspicatus). The study was conducted using a range of concentrations, tested up to the water solubility of the test material. The concentrations of the test material were not maintained in the solutions throughout the entire 72 hour test period, results were expressed as the initial concentration. Under the conditions of the study, the test material exhibited little or no difference on the growth rate of the algae, the ErC50 of the test material is considered to be greater than the water solubility of the test material.
Information on the toxicity of sodium laurate to fresh-water algae, and decanoic acid to saltwater algae, is available in the Human and Environmental Risk Assessment (2003) report on ingredients of European household cleaning products. The 72 hour EC50 value was reported as 53 mg/L for the freshwater algae exposed to sodium laurate and 0.3 mg/L for the saltwater algae exposed to decanoic acid. No information is provided on materials and methods.
The study on dioctyltin oxide (Rufi, 1988b) was performed to the OECD guideline 201. Some deficiencies were present in the study, such as limited reporting and the concentrations of the test material were not maintained throughout the study. As such, the study was assigned a reliability score of 2 and is considered to be the key study to address this endpoint. Since there was no information on materials and methods presented in the Human and Environmental Risk Assessment (2003) report, the data were assigned a reliability score of 4.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.