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Diss Factsheets
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EC number: 206-420-2 | CAS number: 338-83-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- no emission to STP expected
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.131 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.013 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.015 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 66.7 mg/kg food
- Assessment factor:
- 300
Additional information
This substance is not dangerous, and does not need an exposure assessment under REACH. PNECs were derived for use in exposure-based waiving chronic and soil ecotox studies listed in Annex IX. Using available ecotoxicological data, the PNECs were calculated to be 0.0001192 mg/L for Freshwater and 0.00001192 mg/L for Marine Water. For the calculation of the Freshwater and Marine water PNECs; a 21-day NOEC value of 0.00596 mg/L was obtained from PTPA media solubility and toxicity results from a read-across study with Daphnia magna from category member PTBA. Because three acute studies (fish, daphnia and algae) and two chronic studies (algae and daphnia) were available, and the chronic studies were conducted on the organism with the most sensitve acute toxicity (Daphnia), an AF of 50 was applied to the Daphnia chronic NOEC. An assessment factor of 500 was applied to the freshwater NOEC to derive the PNECmarine. For the freshwater (intermittent) PNEC, the lowest of three acute values, the 48-hr EC50 of > 0.00284 mg/L for Daphnia magna, was used with an AF of 100 to obtain a value of 0.0000284 mg/L For Grassland and Agricultural soil, no testing results were available. The EPM method applied to the Freshwater PNEC was used to derive soil PNECs. Using the estimated Koc of 110,000 L/kg, the PNEC for Grassland and Agricultural soil was determined to be 0.136 mg/kg based on wet weight and 0.154 mg/kg based on dry weight. The dry weight value was then divided by a further factor of 10 because the log Kow is > 5. The final PNECsoil is 0.0154 mg/kg dw. Similarly, the PNEC sediment values for freshwater and marine systems were extrapolated using the equilibrium partitioning method (EPM) with the PNECfreshwater and PNECmarine to obtain values of 0.131 and 0.0131 mg/kg dw, respectively. The PNECoral was calculated using read-across of a 28-day repeated dose study of another category member on rat. No effect were observed at the highest dose tested (1000 mg/kg day).
Conclusion on classification
Hazardous to the aquatic environment - acute/short-term: conclusive but not sufficient to classify. No acute toxicity at the limit of water solubility.
Hazardous to the aquatic environment - long-term: conclusive but not sufficient to classify. Not chronically toxic at limit of water solubility. Not persistent in aquatic environment.
M-factor chronic: not applicable.
Hazardous to the ozone layer: conclusive but not sufficient to classify. PTPA is not listed in the Montreal Protocol on Substances that Deplete the Ozone Layer. It does not contain reactive halogens (chlorine or bromine) that could play a role in ozone depletion. PTPA is not hazardous to the ozone layer.
DSD endpoints environment: not classified. No acute toxicity at the limit of water solubility. Not persistent in the aquatic environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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