Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-222-5 | CAS number: 1314-13-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://chesar.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Nanomaterial crystallite and grain size
Administrative data
- Endpoint:
- nanomaterial crystallite and grain size
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study was regarded as scientifically acceptable. Contributions to the widths of Xray diffraction peaks from crystal strain and instrument effects are assumed to be zero. Using XRD the average particle size can be estimated. Specific factors can influence the peak width, such as microstrain, lattice defects and temperature factors. Due to the limited documentation it was not possible to estimate the influence of these factors to the result. Thus, the study was regarded as reliable with restrictions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
- Type of method:
- x-ray diffraction (XRD)
- Details on methods and data evaluation:
- D S-XRD was calculated using Scherrer’s formula. It should be noted that a variety of factors can contribute to the width of a diffraction peak; besides crystallite size, the most important of these usually are inhomogeneous strain and instrumental effects. When Scherrer’s formula is applied, it is assumed that all of these other contributions to the peak width are zero.
Test material
- Test material form:
- solid: nanoform
Constituent 1
- Specific details on test material used for the study:
- Name of test material: Z-cote ®
Code: NM110
Supplier: BASF SE
Surface coating: none
- Substance type: Inorganic
- Physical state: solid powder, nano-form
-Name of test material: Z-cote HP
Code: NM111
Supplier: BASF SE
Surface coating: triethoxycaprylylsilane (2%)
- Substance type: Inorganic
- Physical state: solid powder, nano-form
-Name of test material: NanosunTM
Code: NM112
Supplier: Micronisers
Surface coating: none
- Substance type: Inorganic
- Physical state: solid powder, nano-form
-Name of test material: Zinc Oxide
Code: NM113
Supplier: Sigma-Aldrich
Surface coating: none
- Substance type: Inorganic
- Physical state: solid powder, nano-form
Data gathering
- Instruments:
- Bruker ASX-D8 X-Ray Diffractometer (XRD) using Cu K(alpha) radiation
Results and discussion
Applicant's summary and conclusion
- Executive summary:
CSIRO, 2012 investigated the crystallite size of the nanomaterials. Two methods were used to estimate average crystallite size based on XRD results. Crystallite size of the test samples were calculated using Scherrer’s formula (D S-XRD) and through Rietveld refinement of the diffraction data (D R-XRD). The crystallite size of the test samples determined in two independent experiments calculated using Scherrer’s formula were comparable for all nanomaterial samples. The crystallite sizes determined by XRD were in the range of 24 nm (NM‑112) to 42 nm. Both NM‑110 and NM‑113 have the same crystallite size of 42 nm. The average crystallite size determined by Rietveld refinement yielded larger crystallite sizes. This result could be explained by the fact that the Scherrer’s formula ignores the contributions of width broadening due to strain and instrument effects. If these contributions are non-zero, the crystallite sizes could be larger than those predicted by the Scherrer formula, as revealed by Rietveld refinement of the diffraction data (D‑R XRD). These data were regarded as most reliable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)
Embora a ECHA disponibilize muito material em linha na sua língua, uma parte desta página está disponível apenas em inglês. Mais informações sobreas práticas de multilinguismo da ECHA.
Bem-vindo ao sítio Web da ECHA O navegador Internet Explorer 7 (e versões anteriores) não é totalmente suportado por este sítio Web. Por favor atualize o seu Internet Explorer para uma versão mais recente.
Este sítio Web utiliza cookies a fim de garantir a melhor experiência possível nos nossos sítios Web.
Saiba mais sobre como utilizar cookies.