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EC number: 603-029-2 | CAS number: 125088-75-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- The deviations have no presumed effects on the study.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-Thiophenecarboxylic acid, 3-amino-2,5-dihydro-4-methyl-, methyl ester, 1-oxide
- EC Number:
- 603-029-2
- Cas Number:
- 125088-75-7
- Molecular formula:
- C7H11NO3S
- IUPAC Name:
- 2-Thiophenecarboxylic acid, 3-amino-2,5-dihydro-4-methyl-, methyl ester, 1-oxide
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 102.3 mg/L
- Based on:
- test mat.
- Initial conc.:
- 155.8 mg/L
- Based on:
- ThOD
- Remarks:
- NH4
- Initial conc.:
- 190.4 mg/L
- Based on:
- ThOD
- Remarks:
- NO3
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Key result
- Parameter:
- other: % ThOD NO3 and ThOD NH4
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- Dihydrothiophene ester sulfoxide is considered to be not readily biodegradable.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Dihydrothiophene ester sulfoxide is considered to be not readily biodegradable.
- Executive summary:
The test item Dihydrothiophene ester sulfoxide was investigated for its ready biodegradability in a manometric respirometry test over a period of 28 days. The biodegradation was followed by the oxygen uptake of the microorganisms during exposure. As a reference item sodium benzoate was tested simultaneously under the same conditions as the test item, and functioned as a procedure control.
102.3 mg/L corresponding to an oxygen demand of about 155.8 mg/L (ThODNH4) and 190.4 mg/L (ThODNO3).
The mean biodegradation at test end after 28 days was 0% (ThODNO3, THODNH4).
Therefore, Dihydrothiophene ester sulfoxide is considered to be not readily biodegradable.
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