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Diss Factsheets
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EC number: 241-753-7 | CAS number: 17772-51-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Within 28 days, a degradation rate of 0 % was determined. 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one is considered to be "Not Readily Biodegradable". The reference compound sodium benzoate showed 88 % degradation after 14 days.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
To test for its biodegradability potential of 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one according to EU method C.4 -D “Manometric Respirometry Test“(2008) and the OECD guiedeline 301 F (adopted July 1992), the substance was incubated for 28 days in continuously stirrd 250 mL closed flask (in duplicate) in the dark with an inoculum originally collected from local, predominantly municipal wastewter treatment plant. In this assay, biodegradation was estimated by biological oxygen demand (BOD) over time. BOD was measured daily by a manometer. The incubation temperature was 22 ± 1 °C, pH was 7.4 - 8.0. The concentration of inoculum was 30 mg/L and the one of 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one was a suspension of 100 mg/L. Degradation eas calculated by substracting the amount BOD in the negative (inoculum only) control from that in the substance or positive control at any given time point and divided by the chemical oxygen demand (COD) or thereotical oxygen demand (ThOD). The 28 -days degradation was 0 % and for the positive control (with reference substance) the biodegradation was 88 %. Therefore, 3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one is considered to be “Not Readily Biodegradable“.
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