Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Only basic data given.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1972
Report date:
1972

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Deviations:
yes
Remarks:
only limited data on methodology and results available
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
90583-10-1 (purity 33%)
IUPAC Name:
90583-10-1 (purity 33%)
Details on test material:
- Name of test material (as cited in study report): Sulfuric acid, mono-C8-C14-alkyl ester, ammonium salts
- Physical state: No data
- Analytical purity: 33% a.i.
- Lot/batch No.: No data
- Storage condition of test material: No data

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
oral: gavage
Doses:
5000 mg/kg bw
No. of animals per sex per dose:
10

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Sex:
male
Dose descriptor:
LD50
Effect level:
> 1 650 mg/kg bw
Remarks on result:
other: LD50 given for a.s.
Mortality:
1/10 animals died within the 8 day observation period.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU