Registration Dossier
Registration Dossier
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EC number: 270-337-8 | CAS number: 68425-17-2
Melting point / freezing point
Administrative data
Link to relevant study record(s)
Description of key information
The submission substance is a liquid at room temperature (20 °C), and according to first principles of chemistry, the addition of any substance to pure water will depress the freezing point of pure water to below 0 °C. As such, it is scientifically reasonable to expect the melting point of the submission substance to be less than 0 °C.
However, according to Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7a: Endpoint Specific Guidance, R.7.1.2, the melting point of a substance is environmentally relevant because it determines the temperature at which a substance changes its physical state from solid to liquid and thereby gives an indication of the distribution of the substance within and between the environmental media: water, soil and air. As the submission substance is extremely soluble in water (at least 901530 mg/L), and given its predicted melting point of less than 0 °C, it can reasonably be predicted that the substance will partition into the aquatic compartment. The melting point depression has been calculated by using the cryoscopic method (Petrucci, R.H.; Harwood, W.S.; Herring, F.G. (2002). General Chemistry (8th ed.). Prentice-Hall. pp. 557–558) for a low condensation and a high condensation variant of the UVCB substance, showing that the differences are not too significant (-6.4 °C versus -4.2 °C) and thus, a value of -5 °C for the melting point/freezing point is used for hazard and risk assessment moving forward.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -5 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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