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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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Diss Factsheets
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EC number: 252-043-1 | CAS number: 34454-97-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 96-hour LC50 of C4 sulfonamido alcohol to Mysidopsis bahia was 4.4 mg/L (EPA OPPTS 850.1035, draft version at time of test). Daphnia magna was less sensitive to C4 sulfonamido alcohol toxicity. C4 glycine acid (stable biodegradation product) was not toxic to either species to a limit of 100 mg/L.
Key value for chemical safety assessment
Additional information
C4 sulfonamido alcohol underwent primary biodegradation in an inherent biodegradability test, forming C4 glycine acid as a stable product. Accordingly, toxicity to estuarine and freshwater invertebrates was assessed for both C4 sulfonamido alcohol and C4 glycine acid. The acute toxicity of C4 sulfonamido alcohol to the marine invertebrate Mysidopsis bahia was examined in a 96-hour semi-static test based on EPA OPPTS 850.1035 (then-current draft version of method), with analytical determination of concentrations. The test was based on a draft version of an accepted test guideline and was GLP compliant. It is considered reliable without restriction. In supporting studies, toxicity of C4 sulfonamido alcohol to the freshwater invertebrate Daphnia magna was assessed according to OPPTS 850.1010 and OECD 202, with analytical determination of concentrations. The 48-hour EC50 of C4 sulfonamido alcohol to Daphnia magna was 38 mg/L. In contrast, no effects by C4 glycine acid were observed in limit tests done at 100 mg/L (nominal) with either M. bahia (OPPTS 850.1035) or D. magna (OECD 202). Test soltutions were clear and colorless throughout the test, indicating that the test substance was fully soluble in the test medium. Tests of the C4 glycine acid were not GLP-compliant and were considered reliable with restrictions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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