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EC number: 262-104-4 | CAS number: 60207-90-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 Aug 1999 to 30 Sep 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Version / remarks:
- August 1996
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- December 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EU Mehtod A.4. (Vapour Pressure; See IUCLID Section 4.6)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 104 (Vapour Pressure; See IUCLID Section 4.6)
- GLP compliance:
- yes
- Type of method:
- method according to Siwoloboff
- Key result
- Boiling pt.:
- 99.9 °C
- Atm. press.:
- 0.32 Pa
- Decomposition:
- yes
- Remarks:
- The substance started to decompose in air (oxidative decomposition)
- Decomp. temp.:
- 131 °C
- Remarks on result:
- other: measured value at different pressure. In air the substance is decomposed before reaching the boiling point.
- Conclusions:
- The DSC results indicated that the substance started to decompose in air at 131 °C (oxidative decomposition). Thereafter thermal decomposition occured before the boiling point could be reached, At the reduced pressure of 0.32 Pa the test substance would boil at 99.9 °C.
- Executive summary:
This study was performed in accordance with the OECD TG 103 guideline,the EEC method A.2., the Product Properties Test Guideline, OPPTS 830.7220 and in compliance with GLP. Due to thermal decomposition of the test substance at a temperature lower than that of the boiling point it was not possible to determine the boiling point at normal pressure. Using differential scanning calorimetry it could be determined that:oxidative decomposition starts at about 131 °C.The boiling point at reduced pressure is taken from the report on vapour pressure curve:the boiling point at 0.32 Pa is 99.9 °C.
Reference
RESULTS USING DIFFERENTIAL SCANNING CALORIMETRY
The observations strongly suggested that the substance was decomposing and that this decomposition was occurring before the boiling point could be reached. In order to interpret these observations with the test substance, additional investigations were performed using DSC. Finally, a second control determination of the boiling point of toluene was then performed using the same conditions as before. A boiling point of 109.5 °C was determined. Using the measured atmospheric pressure, 97.7 kPa, the temperature correction factors given in the OECD TG 103 guideline, the Sidney-Young number-value-equation, and the boiling point of toluene at standard pressure, it was possible to calculate the corrected boiling point, 109.3 °C, of toluene at the measured atmospheric pressure. The experimentally determined average boiling point of toluene, 109.6 °C, agreed well with this calculated, corrected value.
In order to interpret the observations made, additional investigations were performed under GLP, using DSC, by the testing facility, Physical Chemistry, Solvias AG, Basel (formerly: Physics, Novartis Services, Basel ). A Perkin Elmer 7 Series Thermal Analysis System was used. The thermal behaviour of the test substance was investigated, not only in air, but also under a nitrogen atmosphere, using a heating rate of 10.0 °C / minute, starting from 25.0 °C. Under nitrogen an intense decomposition began at around 353 °C. Prior to this temperature, there was no indication of boiling. In air, however, an initial decomposition was observed in the range 131 °C to 264 °C. This was followed by a second decomposition, which started at about 335 °C. As is, however, typical for oxidative decomposition, these temperatures are slightly dependent upon the ratio of test substance to air present in the DSC system. The nature of this initial decomposition must be oxidative as it was not observed under nitrogen. In neither curve, however, was any evidence of boiling observed.
RESULTS FROM A VAPOUR PRESSURE STUDY
This study was performed under GLP, in accordance with the OECD TG 104 guideline and the EEC method A.4. At 99.9 °C the test substance was determined to have a vapour pressure of 0.32 Pa. Therefore, at the reduced pressure of 0.32 Pa the test substance would boil at 99.9 °C.
Description of key information
Due to thermal decomposition of the test substance at a temperature lower than that of the boiling point it was not possible to determine the boiling point at normal pressure using the Siwoloboff method. Using differential scanning calorimetry it could be determined that:oxidative decomposition starts at about 131 °C.The boiling point at reduced pressure is taken from the report on vapour pressure curve:the boiling point at 0.32 Pa is 99.9 °C, Das 1999.
Key value for chemical safety assessment
Additional information
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