Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-229-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
General considerations
CdSSe is a highly insoluble Cd-compound. This is demonstrated by the transformation-dissolution tests, where after 7 days shaking at pH6 only 0.026% of the Cd in the substance goes into solution; after 28 days of testing, dissolution was still very low: 0.028% of total Cd contained in the substance. For this reason, the ecotoxicity results obtained on soluble Cd-compounds are considered not relevant for CdSSe. Reference is made to standardised testing, applied on CdTe, another Cd-compound with limited solubility in water. The solubility of CdTe is however higher than the one of CdSSe, so this dataset on CdTe can be considered as a worst case for the CdSSe.
For PNEC derivation, a basic assumption made in this hazard assessment and throughout the CSRs on cadmium and cadmium compounds, (in accordance to the same assumption made in the EU RA process), is that the causative factor for ecotoxicity of these substances is the Cd++ion. As a consequence, for the setting of PNEC's for these substances, the generic PNEC as derived for the Cd++ion is used, and is always referring to the Cd ion concentration.
However, Cd-substances can differ significantly in their solubility, i.e. their capacity to release cadmium ions into (environmental) solution. That effect is checked eventually in the transformation/dissolution (T/D) tests and may result in different environmental hazard and, consequently, different classification for aquatic effect.
Classification
CdSSe is specifically excempted from classification under DSD 67/548/EEC.The reason for this non-classification is the insolubility of the substance.
For CLP, data were generated to check this existing classification against the CLP rules. To this end, transformation/dissolution (T/D) tests were performed on the CdSSe, and reference was made towards newly generated T/D and ecotoxicity data obtained on another sparingly soluble Cd-compound, i.e. CdTe. By comparing T/D data between CdSSe and CdTe, and referring to aquatic effect levels observed for CdTe, the aquatic hazard of the CdSSe could be assessed as follows:
Acute aquatic classification
Standard ecotoxicity testing on CdTe revealed a lowest EC50 value of 1.14 mg CdTe/Lobserved for Daphnia magna (resulting in no acute classification of CdTe). T/D testing on CdTe demonstrated the sparingly soluble character of this substance (3.2% of Cd solubilised after 7days in pH 6 medium, which is maximising Cd-solubilisation in the relevant pH range 6 -8.5). The solubility of Cd from CdSSe was however even much lower than the solubility of Cd in CdTe: after 7 days only 0.026 % of the Cd was solubilised from CdSSe at pH 6. Considering a) the lowest EC50 value of CdTe of 1.14mg/l, and b) the >100x lower solubility of Cd in CdSSe, as compared to CdTe, it is concluded that also CdSSe is not classified for acute aquatic effect.
Chronic aquatic classification
Standard ecotoxicity testing on CdTe revealed a lowest NOEC value of 0.2 mg CdTe/L observed forDaphnia magna,resulting in classificationas
"chronic3"of CdTe - in this respect it is noted that Cadmium compounds are considered as being "equivalent to rapidly degradable" based on their rapid removal from the water column, see section 4.6.). T/D testing on CdTe demonstrated the sparingly soluble character of this substance (3.8% of Cd solubilised after 28 days in pH 6 medium, which is maximising Cd-solubilisation in the relevant pH range 6 -8.5). From T/D tests, it was shown that the solubility of Cd from CdSSe was however even much lower than the solubility of Cd in CdTe: after 28 days only 0.028 % of the Cd was solubilised from CdSSe at pH 6. Considering a) the lowest NOEC value of CdTe of 0.2mg/l, and b) the >100x lower solubility of Cd in CdSSe, as compared to CdTe, it is concluded that CdSSe is not classified for chronic aquatic effect.
This analysis confirms the non-classification of CdSSe for aquatic effects under DSD.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.