7-benzamido-4-hydroxynaphthalene-2-sulphonic acid

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

accepted calculation method

Justification for type of information:

Data is from prediction model by US EPA

Qualifier:

according to guideline

Guideline:

other: Modeling database

Principles of method if other than guideline:

Prediction done using ECOSAR v.1.11 model

GLP compliance:

no

Specific details on test material used for the study:

- Name of test material: 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid
- Molecular formula: C17 H13 N O5 S
- Molecular weight: 343.3577 g/mol
- Smiles notation: c1ccc(cc1)C(=O)Nc2ccc3c(c2)cc(cc3O)S(=O)(=O)O
- InChl: 1S/C17H13NO5S/c19-16-10-14(24(21,22)23)9-12-8-13(6-7-15(12)16)18-17(20)11-4-2-1-3-5-11/h1-10,19H,(H,18,20)(H,21,22,23)
- Substance type: Organic
- Physical state: Solid

Test organisms (species):

other: Fish

Test type:

static

Water media type:

freshwater

Total exposure duration:

96 h

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

10 791.128 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Validity criteria fulfilled:

not specified

Conclusions:

The lethal concentration LC50 value for the substance was estimated to be 10791.128 mg/l for fish for 96 hr exposure duration. Based on this lethal value it can be concluded that the substance7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6)can be considered to be non toxic to aquatic environment and thus it become not classified as per the CLP classification criteria.

Executive summary:

Using the EPI Suite ECOSAR version 1.11, the short term toxicity on fish was predicted for test substance 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6)on the basis of effects observed in a static freshwater system. The lethal concentration LC50 value for the substance was estimated to be 10791.128 mg/l for fish for 96 hr exposure duration. Based on this lethal value it can be concluded that the substance 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6) is likely to be non toxic to aquatic environment and thus it can be considered not classified as per the CLP classification criteria.

Description of key information

Using the EPI Suite ECOSAR version 1.11, the short term toxicity on fish was predicted for test substance 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6)on the basis of effects observed in a static freshwater system. The lethal concentration LC50 value for the substance was estimated to be 10791.128 mg/l for fish for 96 hr exposure duration. Based on this lethal value it can be concluded that the substance 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6) is likely to be non toxic to aquatic environment and thus it can be considered not classified as per the CLP classification criteria.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

10 791.128 mg/L

Additional information

Using the EPI Suite ECOSAR version 1.11, the short term toxicity on fish was predicted for test substance 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6)on the basis of effects observed in a static freshwater system. The lethal concentration LC50 value for the substance was estimated to be 10791.128 mg/l for fish for 96 hr exposure duration. Based on this lethal value it can be concluded that the substance 7-(benzoylamino)-4-hydroxynaphthalene-2-sulfonic acid (132-87-6) is likely to be non toxic to aquatic environment and thus it can be considered not classified as per the CLP classification criteria.