Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-878-0 | CAS number: 2272-11-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48-h EC50 value for monoethanolamine in Daphnia magna is 65 mg/L, after correction for molecular weight an effect concentration of 366 mg/L for monoethanolamine oleate will be used in the assessment.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 366
Additional information
No short-term studies with invertebrates are available for monoethanolamine oleate. A GLP-compliant Directive 92/69/EEC, C.2. guideline study with Daphnia magna is available for one of its starting materials, monoethanolamine (Huels, 1997). Monoethanolamine oleate is the salt of monoethanolamine and oleic acid. As oleic acid is exempted for registration according to Annex V of REACH Directive 2006/121/EC, the focus is only on the monoethanolammmonium cation of monoethanolamine oleate (for more details see reporting format for the analogue approach in Appendix).
Daphnids (20/dose) were exposed to nominal concentrations of 3 to 1000 mg/L under semi-static conditions for 48 hours, the test concentrations were analytically verified and were within 80% of nominal concentrations. The 48-h EC50 value is 65 mg/L (based on nominal concentrations), a safety factor need not to be applied to this value. Instead, the effect concentration will be corrected for molecular weight. An effect concentration of 366 mg/L for monoethanolamine oleate will be used in the assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
