Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 825-116-6 | CAS number: 24704-41-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The complex EDTA-CoH2 consist of the organic moiety EDTA, the central atom Co2+ and the protons. As protons are known to be non-sensitizing only the EDTA-Co complex must be regarded as dangerous. In general, the complex with the chelated Co2+ ion should be less sensitizing than the free Co2+ ion. Based on that and that the complex EDTA-Co has an average stability, a worst-case assessment where the EDTA-CoH2 complex dissociate in its components can be done and so a read-across is possible to free EDTA and other Co2+ compounds. The latter are known to be possible sensitizers. Most soluble cobalt (2 +) salts are classified as skin sensitizing.
Many cobalt(II) compounds and cobalt are known for the fact, that they may cause an allergic skin reaction.
The following substances are, inter alia, classified with H317: cobalt (Index number 027-001-00-9), cobalt dichloride (Index number 027-004-00-5), cobalt sulfate (Index number 027-005-00-0), cobalt sulfide (Index number 027-003-00-X), cobalt di(acetate) (Index number 027-006-00-6), cobalt dinitrate (Index number 027-009-00-2) and cobalt oxide (Index number 027-002-00-4).
Thus as a worst case approach the substance to be registered is classified accordingly as well.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
