Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 942-422-6 | CAS number: -
Consumer Uses
Documentsopen allclose all
Consumer uses
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- GES10 - Consumer end-use of cosmetics
- Environmental release category (ERC):
- ERC8a: Widespread use of non-reactive processing aid (no inclusion into or onto article, indoor)
Contributing activity / technique for consumers
- Name of activity / technique:
- GES10 - Consumer end-use of cosmetics (outside scope - Regulation (EC) 1907/2006: Article 1, paragraph 5(c))
- Product category (PC):
- PC 0: Other: not applicable
- Substance supplied to this use in the form of:
- in a mixture
- Subsequent service life relevant to this use:
- no
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to consumer activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Conditions and measures related to external treatment of waste (including article waste)
Other conditions affecting environmental exposure
Releases to waste and the environment
ReleasesWasteEnvirRepopen allclose all
Exposure of the environment
ExpEnvirRelatedToRepopen allclose all
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
ExpRelatedToRepopen allclose all
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Consumer uses
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- GES7 - Consumer end-use of air care products
- Environmental release category (ERC):
- ERC8a: Widespread use of non-reactive processing aid (no inclusion into or onto article, indoor)
Contributing activity / technique for consumersopen allclose all
- Name of activity / technique:
- CS1 Air fresheners aerosol : aqueous, non-aqueous, concentrated (mini-aerosol, Timed release aerosol) ; AISE C17
- Product category (PC):
- PC 3: Air care products
- Name of activity / technique:
- CS2 Air fresheners non aerosol [a) perfume in/on solid substrate (gel), diffusers (heated) AISE C18; [b) candles AISE C18]
- Product category (PC):
- PC 3: Air care products
- Substance supplied to this use in the form of:
- in a mixture
- Subsequent service life relevant to this use:
- no
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to consumer activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Conditions and measures related to external treatment of waste (including article waste)
Other conditions affecting environmental exposure
Releases to waste and the environment
ReleasesWasteEnvirRepopen allclose all
Exposure of the environment
ExpEnvirRelatedToRepopen allclose all
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
ExpRelatedToRepopen allclose all
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenConsumersRepopen allclose all
Contributing scenario for the consumers
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 1.004 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- aa8bf61c-dd4a-4214-8f0b-9f347b5c94df
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.216 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.298 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Consumer uses
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- GES6 - Consumer end-use of washing and cleaning products
- Environmental release category (ERC):
- ERC8a: Widespread use of non-reactive processing aid (no inclusion into or onto article, indoor)
- ERC8d: Widespread use of non-reactive processing aid (no inclusion into or onto article, outdoor)
Contributing activity / technique for consumersopen allclose all
- Name of activity / technique:
- CS1 Laundry and dish washing products [a) laundry regular AISE C1; b) laundry compact AISE C2; c) fabric conditioners AISE C3; d) Laundry additives AISE C4; e) Hand diswashing AISE C5; f) Machine diswashing AISE C6; g) Laundry aids AISE C12]
- Product category (PC):
- PC 35: Washing and cleaning products
- Name of activity / technique:
- CS2 Cleaners, liquids [a) Surface cleaners (liquid, powder, gel neat) AISE C7; c) Carpet cleaners AISE C11; d) Wipes AISE C15; e) High pressure washers/cleaners AISE C21 (PC 35)
- Product category (PC):
- PC 35: Washing and cleaning products
- Name of activity / technique:
- CS2 Cleaners, liquids [b) Toilet cleaners; AISE C8]
- Product category (PC):
- PC 35: Washing and cleaning products
- Name of activity / technique:
- CS2 Cleaners, liquids [f) Automotive care (liquid) ; AISE C22]
- Product category (PC):
- PC 35: Washing and cleaning products
- Name of activity / technique:
- CS3 Cleaners, trigger sprays [a) Surface cleaners AISE C7; b) Oven cleaners AISE C10; c) Carpet cleaner AISE C11]
- Product category (PC):
- PC 35: Washing and cleaning products
- Name of activity / technique:
- CS3 Cleaners, trigger sprays [d) Automotive care (spray) ; AISE C22]
- Product category (PC):
- PC 35: Washing and cleaning products
- Subsequent service life relevant to this use:
- no
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to consumer activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Conditions and measures related to external treatment of waste (including article waste)
Other conditions affecting environmental exposure
Releases to waste and the environment
ReleasesWasteEnvirRepopen allclose all
Exposure of the environment
ExpEnvirRelatedToRepopen allclose all
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
ExpRelatedToRepopen allclose all
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenConsumersRepopen allclose all
Contributing scenario for the consumers
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.016 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.143 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- 9b1dc599-1b87-420b-b8ab-e8b200ebe1e8
Product (article) characteristics
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.104 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.143 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- 29893a4f-8b19-4fac-851e-d7ca62e5aa27
Product (article) characteristics
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.052 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.429 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- c345d077-fa3b-49ef-8474-2e2f19e73881
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.063 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.357 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- a557546c-bd25-4432-98a8-8845b097f242
Product (article) characteristics
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.515 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.143 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- e0cd787d-2dfc-4b09-9bd0-e14af87d2c48
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.206 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.072 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
Reference
ExposureEstimationopen allclose all
Consumer uses
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- GES8 - Consumer end-use of biocides (indoor and outdoor use)
- Environmental release category (ERC):
- ERC8a: Widespread use of non-reactive processing aid (no inclusion into or onto article, indoor)
- ERC8d: Widespread use of non-reactive processing aid (no inclusion into or onto article, outdoor)
Contributing activity / technique for consumersopen allclose all
- Name of activity / technique:
- CS1 Insecticides, spray neat, AISE C19
- Product category (PC):
- PC 8: Biocidal products (e.g. disinfectants, pest control)
- Name of activity / technique:
- CS1 Insecticides, liquid electric, AISE C19
- Product category (PC):
- PC 8: Biocidal products (e.g. disinfectants, pest control)
- Name of activity / technique:
- CS2 Repellents; AISE C19
- Product category (PC):
- PC 8: Biocidal products (e.g. disinfectants, pest control)
- Subsequent service life relevant to this use:
- no
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to consumer activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Conditions and measures related to external treatment of waste (including article waste)
Other conditions affecting environmental exposure
Releases to waste and the environment
ReleasesWasteEnvirRepopen allclose all
Exposure of the environment
ExpEnvirRelatedToRepopen allclose all
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
ExpRelatedToRepopen allclose all
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenConsumersRepopen allclose all
Contributing scenario for the consumers
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.18 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.015 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- aa6b12fb-2c8a-4ffd-961c-d8d75657b654
Product (article) characteristics
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.06 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- c85d9704-d659-4c83-83a7-82fe2e40d28f
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.6 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0.24 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- other: ConsExpo Web
- Version of exposure estimation tool:
- 1.0.3
Reference
ExposureEstimationopen allclose all
Consumer uses
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- GES9 - consumer end-use of polishes and wax blend
- Environmental release category (ERC):
- ERC8a: Widespread use of non-reactive processing aid (no inclusion into or onto article, indoor)
Contributing activity / technique for consumersopen allclose all
- Name of activity / technique:
- CS1 Furniture, floor & leather care: wax/cream; (floor, furniture, shoes) ; AISE C20
- Product category (PC):
- PC 31: Polishes and wax blends
- Name of activity / technique:
- CS2 Furniture, floor & leather care: spray; (furniture, shoes) ; AISE C20
- Product category (PC):
- PC 31: Polishes and wax blends
- Substance supplied to this use in the form of:
- in a mixture
- Subsequent service life relevant to this use:
- no
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to consumer activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Other conditions
Conditions and measures related to external treatment of waste (including article waste)
Other conditions affecting environmental exposure
Releases to waste and the environment
ReleasesWasteEnvirRepopen allclose all
Exposure of the environment
ExpEnvirRelatedToRepopen allclose all
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
ExpRelatedToRepopen allclose all
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenConsumersRepopen allclose all
Contributing scenario for the consumers
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 0.081 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.143 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Contributing scenario for the consumers
- Linked contributing activity:
- f1ba018e-c2ff-4be8-8a38-3a7c34bb5328
Product (article) characteristics
- Physical form of the used product:
- liquid
OtherProductCharacteristicsRepopen allclose all
Amounts used (or contained in articles), frequency and duration of use/exposure
ConditionsOfUseRepopen allclose all
Information and behavioural advice for consumers
ConditionsOfUseIndicatedInAdviceRepopen allclose all
Other conditions affecting consumers exposure
OtherConditionsAffectingConsExpRepopen allclose all
Exposure of consumers
- Assessment entity name:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized - AE1
- Related composition:
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Reaction products of ((5E)-5-ethylidenebicyclo[2.2.1]hept-2-ene and (5Z)-5-ethylidenebicyclo[2.2.1]hept-2-ene) and 2-methyl-1,3-butadiene, epoxidized
- Additional information:
This UVCB substance is composed of eleven constituents of similar structural and functional groups. For human health hazard and risk assessment, the substance can be assessed as a single entity, with a high degree of confidence, by employing the highest vapour pressure and molecular weight for use in exposure estimation. This can be compared against reference values derived from toxicity data generated on the bulk material.
For environmental assessment, relevant data needed for exposure assessment are available on each constituent (i.e. water solubility, partition coefficient, adsorption/desorption, hydrolysis and aquatic toxicity studies). Data on vapour pressure and biotic degradation (ready biodegradability) are only available on the bulk material, indicating that the substance is of low volatility and not readily biodegradable. Two groups of constituents have been identified that share the same environmental profile, each of which have contrasting profiles relating to it's environmental fate and behaviour in different compartments, therefore the most suitable approach for environmental risk assessment is to assess each group of constituents individually. This is consistent with the approach for performing risk assessments of complex substances using the block method (ECHA, ECHA/2008/02/SR30).
Assessment Entity - AE1:
This assessment entity will be used for human health exposure assessment and risk characterisation, which are based on bulk measurements of toxicology endpoints and vapour pressure.
Constituent Number Assessment Entity Constituent Name Molecular Weight Typical Concentration (% w/w) Vapour Pressure (Pa) Partition Coefficient (Log Pow) Water Solubility (mg/L) Hydrolytic Half-Life (d) Readily Biodegradable (Y/N) Adsorption Coefficient (Log Koc) Fish LC50 (mg/L) Daphnid EC50 (mg/L) Algal EC50 (mg/L) 1 1 (1'RS,2RS,2'RS,3RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 2 1 (1'RS,2SR,2'RS,3RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 3 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 4 1 (1RS,2RS,4RS,6SR,8RS,9RS,11E)-11-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 5 1 (1'RS,2'RS,7'RS,8'RS)-3,5'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 6 1 (1'RS,2'RS,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I. 0.716 3.85 8.3 0.20 N 2.964 2.01 2.59 1.83 7 1 (1'RS,2SR,2'RS,3SR,7'RS,8'RS)-3,4'-dimethylspiro[oxirane-2,9'-tricyclo[6.2.1.02,7]undec[4]ene] 204.31 C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
8
1
(1RS,2RS,4RS,6SS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
9
1
(1RS,2RS,4SR,6RS,8RS,9RS,10Z)-10-ethylidene-4-methyl-5-oxatetracyclo[7.2.1.02,8.04,6]dodecane
204.31
C.B.I.
0.716
3.85
8.3
0.20
N
2.964
2.01
2.59
1.83
10
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10RS)-3',6-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
11
2
(1RS,2RS,3'RS,4SR,6RS,8RS,9RS,10R)-3',4-dimethylspiro[5-oxatetracyclo[7.2.1.02,8.04,6]dodecane-10,2'-oxirane]
220.31
C.B.I.
0.716
2.45
70.8
0.20
N
2.099
12.5
7.32
25.6
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimate:
- 1.252 mg/m³
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimate:
- 0.143 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
- Type of exposure:
- oral (external) long-term intake
- Exposure estimate:
- 0 mg/kg bw/day
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA consumers
- Version of exposure estimation tool:
- 3.1 (R15)
Reference
ExposureEstimationopen allclose all
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
