Registration Dossier
Registration Dossier
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EC number: 284-716-0 | CAS number: 84962-20-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The animals did not show any signs of systemic toxicity during the course of the study and no cases of mortality were observed. On day 3 and day 4,all animals treated with the test item concentrations of 10, 25, and 50% showed an erythema of the ear skin (Score 1). The body weight of the animals was within the range commonly recorded for animals of this strain and age.
Migrated from Short description of key information:
The sensitization potential of Phosphoric acid, mixed esters with Bu.Alc. and Ethylene glycol was investigated according to OECD Guideline 429. The test item concentrations chosen for the LLNA test were 10, 25, 50 %.
Justification for selection of skin sensitisation endpoint:
Guideline-conform study under GLP without deviations.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Phosphoric acid, mixed esters with Bu.Alc. and Ethylene glycoldid not show skin sensitizing properties in the Local Lymph Node Assay according to the current OECD guidelines. Allergic skin reactions or case reports of acute contact dermatitis to the substance have not been described in the literature. Therefore, the substance does not have to be classified as a skin sensitizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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