Alkyl iodides, C8-14, γ-ω-perfluoro

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2002

Report date:

2002

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-

IUPAC Name:

1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-

Constituent 2

Reference substance name:

3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecan-1-ol

EC Number:

211-648-0

EC Name:

3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecan-1-ol

Cas Number:

678-39-7

IUPAC Name:

3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecan-1-ol

Details on test material:

- Name of test material (as cited in study report): 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

72 h

Test conditions

Reference substance (positive control):

yes

Remarks:

Potassium dichromate

Results and discussion

Effect concentrations

Remarks on result:

other: Please see executive summary

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

In this study 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro- was found not to inhibit the growth of the freshwater green alga Scenedesmus subspicatus at the saturated solution level, containing 0.20 mg/L (initially measured concentration).

Executive summary:

The acute toxicity of 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro- (batch number P00/001) to the unicellular freshwater green alga Scenedesmus subspicatus was determined according to the principles of OECD-Guideline 201, at DR.U.NOACK-LABORATORIUM FÜR ANGEWANDTE BIOLOGIE in 31157 Sarstedt, Germany from April 01 to 04, 2002.

The study was conducted under static conditions over a duration of 72 hours with an initial cell density of nominally 104 cells/mL and a saturated solution as limit concentration, containing 0.20 mg/L. For the preparation of the saturated solution a suspension with a nominal loading of 100 mg/L was shaken for 96 h and centrifuged. The clear supernatant was used for the test.

Test vessels were coated with the test item for 14 days before the test started. Three replicates were tested for the limit concentration and 6 replicates for control. The test item was clearly dissolved throughout the test. Microscopic evaluation of the cells at the start and end of the incubation period revealed no morphological abnormalities. Water quality parameters of pH-value, measured at 0 and 72 h, and room temperature, measured continuously, were determined to be within the acceptable limits.

The concentration of the active ingredient 1-Decanol, 3,3,4,4,5,5,6,6, 7,7,8,8,9,9,10,10,10-heptadecafluoro- were analysed at the limit concentration level at test start and test end. Details of the analytical results are given in Part 10. The initially measured concentration of 1-Decanol, 3,3,4,4,5,5,6,6, 7,7,8,8,9,9,10,10,10-heptadecafluoro- was 0.20 mg/L. At the end of the test the concentration of the test item was below the detection limit of 0.009 mg/L. Sorption to the glass walls of the test vessels is unlikely as the walls were already pre-coated for 14 days before the test has started.