Registration Dossier
Registration Dossier
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EC number: 614-295-4 | CAS number: 68131-40-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 03 September 2009 - 09 November 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to internationally accepted guidelines and to GLP.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: turbidity
- Water solubility:
- 1.1 mg/L
- Temp.:
- 25 °C
- pH:
- > 6 - < 7.2
- Remarks on result:
- other: Temperature was assumed to be 25°C however, this was not specified.
- Details on results:
- The water solubility of Softanol 30 was determined by turbidimetry to be 1.1 mg/l (mean of 1.2 and 1.0 mg/l).
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of Softanol 30 was determined by turbidimetry to be 1.1 mg/l. Temperature was assumed to be 25°C however, this was not specified.
Reference
A solubility of approximately 10 to 100 mg/l was estimated. Subsequent method development work indicated that the test substance dispersed readily in water and that this estimation may have been falsely high (as the dispersion of the relatively small amount of test substance in the large volume of water may have indicated dissolution). Given this observation, and the likelihood that this would preclude separation of undissolved material, it was considered that turbidimetric determination of solubility would be the best approach
Description of key information
Water solubility of Softanol 30 was determined by turbidimetry to be 1.1 mg/L (mean of 1.2 and 1.0 mg/L).
Key value for chemical safety assessment
- Water solubility:
- 1.1 mg/L
- at the temperature of:
- 25 °C
Additional information
A solubility of approximately 10 to 100 mg/l was estimated. Subsequent method development work indicated that the test substance dispersed readily in water and that this estimation may have been falsely high (as the dispersion of the relatively small amount of test substance in the large volume of water may have indicated dissolution). Given this observation, and the likelihood that this would preclude separation of undissolved material, it was considered that turbidimetric determination of solubility would be the best approach.
The temperature at which the solubility test was carried out is assumed to be 25°C, although this was not specifically stated in the report.
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