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EC number: 208-591-9 | CAS number: 534-17-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- HYPOTHESIS FOR THE ANALOGUE APPROACH
Cesium carbonate completely dissociates in water forming cesium cation and the corresponding carbonate anion. Thus, cesium salts with different anion moieties were found to be suitable candidates for read-across. (Eco)toxicological properties were extrapolated to different endpoints by using the lowest effect concentration.
For further information, please refer to the read-across justification in IUCLID section 13. - Reason / purpose for cross-reference:
- read-across source
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 20 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: calculated for Cs
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: calculated for Cs
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 107 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: calculated for Cs
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 24 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: calculated for Cs2CO3
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 12 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: calculated for Cs2CO3
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 130 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: calculated for Cs2CO3
- Basis for effect:
- growth rate
Reference
Description of key information
A toxicity study to aquatic algae and cyanobacteria with cesium carbonate is not available. Consequently, read-across was applied using data from cesium hydroxide monohydrate. Under the conditions of this acute algal growth inhibition test on Pseudokirchneriella subcapitata the observed endpoints for the effect of cesium hydroxide monohydrate based on the growth rate were the following: 72h EC50 value: 133.99 mg test item/L; 72h NOEC value: 12.5 mg test item/L and 72h LOEC value: 25 mg test item/L.
Based on these data the 72h-EC50 calculated for cesium was 107 mg/L, the 72h-LOEC was 20 mg/L and the 72h NOEC was 10 mg/L and for cesium carbonate the calculated 72h-EC50 value was 131 mg/L, the 72h-LOEC was 24 mg/L and the 72h NOEC was 12 mg/L. All reported biological results are related to the nominal concentrations.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 131 mg/L
- EC10 or NOEC for freshwater algae:
- 12 mg/L
Additional information
A toxicity study to aquatic algae and cyanobacteria with cesium carbonate is not available. Consequently, read-across was applied using study from cesium hydroxide monohydrate.
An Acute Growth Inhibition Test of cesium hydroxide monohydrate on Algae (Pseudokirchneriella subcapitata) over an exposure period of 72 hours in a static system was assessed according to OECD Guideline 201 and EU method C.3. Five different concentrations arranged in a geometric series and an untreated control group were tested in the main study. The highest concentration was 100 mg/L. The following concentrations were used in the main study: 6.25; 12.5; 25, 50 and 100 mg/L. The shape of the algal cells growing was obviously not affected. Under the conditions of this acute algal growth inhibition test on Pseudokirchneriella subcapitata the observed endpoints for the effect of cesium hydroxide monohydrate based on the growth rate were the followings: 72h EC50 value: 133.99 mg test item/L; 72h NOEC value: 12.5 mg test item/L and 72h LOEC value: 25 mg test item/L.
Based on these data the 72h-EC50 calculated for cesium was 107 mg/L, the 72h-LOEC was 20 mg/L and the 72h NOEC was 10 mg/L and for cesium carbonate the calculated 72h-EC50 value was 131 mg/L, the 72h-LOEC was 24 mg/L and the 72h NOEC was 12 mg/L.
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