Registration Dossier
Registration Dossier
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EC number: 253-506-0 | CAS number: 37439-34-2
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- other: (Q)SAR
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: Company in-house data
- Title:
- OECD Toolbox Application ver. 1.1.
- Author:
- Gerard van Brakel
- Year:
- 2 009
- Bibliographic source:
- OECD
Materials and methods
Test guideline
- Guideline:
- other: Chapter R6: (Q)SARs and grouping of chemicals
- Principles of method if other than guideline:
- General model for skin sensitisation
- Type of study:
- other: (Q)SAR
Test material
- Reference substance name:
- Sodium 3,5,6-trichloropyridin-2-olate
- EC Number:
- 253-506-0
- EC Name:
- Sodium 3,5,6-trichloropyridin-2-olate
- Cas Number:
- 37439-34-2
- Molecular formula:
- C5HCl3NONa
- IUPAC Name:
- sodium 3,5,6-trichloropyridin-2-olate
- Details on test material:
- - Chemical name: 2(1H)-pyridinone, 3,5,6-trichloro-, sodium salt
- Smiles notation (if other than submission substance): Cl(=O)C(Cl)=CC(Cl)=C(Cl)N1
Constituent 1
Results and discussion
Any other information on results incl. tables
The (Q)SAR predicts a skin sensitization of 1.50, which means that the material may be skin sensitizing.
Applicant's summary and conclusion
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information
- Conclusions:
- Based on the (Q)SAR results the substance may be skin sensitizing. However, many years of experience has not shown any cases of skin sensitisation. Therefore, this endpoint is not considered good enough to classify as sensitising.
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