Nonane

PBT assessment

PBT assessment: overall result

PBT status:

the substance is not PBT / vPvB

Justification:

Persistence (P) Assessment:

A substance is not considered to be persistent if it can be demonstrated that it has potential to degrade (via photolysis, hydrolysis and/or biodegradation)

Several ready biodegradability studies are available demonstrating nonane to be readily biodegradable with degradation rates of up to 100% after 15 to 25 days (e.g. Solano-Serena et al. 1999, Nagata and Kondo 1977).

Therefore, the substance does not meet the Persistent (P) or very Persistent (vP) criteria.

Bioaccumulation (B) Assessment:

An evaluation of representative hydrocarbon structures indicates no structures meet the Bioaccumulative (B) or very Bioaccumulative (vB) criteria. A BCF was estimated to be 105 (HSPA consortium 2009). Based on the screening criteria for bioaccumulation stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008), nonane is considered unlikely to be bioaccumulative.

Toxicity (T) Assessment:

Environmental Toxicity:

No representative structures were identified as PBT or vPvB, therefore a toxicity assessment is not needed. None of the measured or calculated data for nonane is within the criteria for toxicity stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008). Therefore this substance is not considered toxic (T).

 

Human Health Hazards Assessment (T)

Carcinogenicity:

The available data on nonane do not warrant classification for carcinogenicity under GHS/CLP.

Mutagenicity:

The available data indicate that nonane is not genotoxic or mutagenic and do not warrant classification for carcinogenicity under GHS/CLP.

Reproductive Toxicity:

 

There is no evidence that nonane causes reproductive or developmental toxicity. The available data indicate that nonane is not toxic to reproduction and does not warrant classification under GHS/CLP.