Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Workers - Hazard via inhalation route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
3 mg/m³
Acute/short term exposure
DNEL related information

Workers - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
3.05 mg/kg bw/day
Most sensitive endpoint:
developmental toxicity / teratogenicity
DNEL related information
Overall assessment factor (AF):
525
Modified dose descriptor starting point:
NOAEL
Acute/short term exposure
DNEL related information

Workers - Hazard for the eyes

Additional information - workers

Workers might be exposed to silicic acid, aluminum magnesium salt during the manufacturing process.

 

Workplace exposure to silicic acid, magnesium aluminum salt (MAS) is neither regulated on the EU level nor in any of the member states. Therefore, the limits of inhalation exposure to MAS at the workplace are based on the general limit values for dust (TRGS 900, June 2008): The existing OEL for dust is 3 mg/m3(alveolar fraction) and 10 mg/m3(respirable fraction). It is proposed to adopt the more critical value of 3 mg/m3as DNEL. This approach is in compliance with the ECHA "Guidance on information requirements and chemical safety assessment. Chapter R.8: Characterisation of dose [concentration]-response for human health", May 2008.

 

Depending on the production parameters applied in the precipitation and filtration process, a wide range of silicic acid, aluminium magnesium salt (MAS) products with different chemical properties can be produced (see chapter 2.1). Particularly, the variable content of sodium ions and variable pH values (up to pH 10.6) of MAS products have to be considered. Due to their chemical properties, MAS products might cause irritating effects to the skin and the eyes. This potential hazard is addressed by the advice to wear suitable personal protective equipment, including goggles, gloves and protective clothing.

General Population - Hazard via inhalation route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
0.002 mg/m³
Most sensitive endpoint:
repeated dose toxicity
DNEL related information
Overall assessment factor (AF):
150
Dose descriptor:
NOAEC
Acute/short term exposure
DNEL related information

General Population - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
1.52 mg/kg bw/day
Most sensitive endpoint:
developmental toxicity / teratogenicity
DNEL related information
Overall assessment factor (AF):
1 050
Modified dose descriptor starting point:
NOAEL
Acute/short term exposure
DNEL related information

General Population - Hazard via oral route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
1.52 mg/kg bw/day
Most sensitive endpoint:
developmental toxicity / teratogenicity
DNEL related information
Overall assessment factor (AF):
1 050
Modified dose descriptor starting point:
NOAEL
Acute/short term exposure
DNEL related information

General Population - Hazard for the eyes

Additional information - General Population

Silicic acid, aluminium magnesium sodium salt is used in inclusion into or onto matrices. Therefore a risk potential to the general population is not expected at all.