Registration Dossier
Registration Dossier
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EC number: 447-060-8 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The following values were obtained from the test:
EC50 (biomass): 57.6 mg/L,
EC50 (growth rate): 85.4 mg/L,
NOEC: 42.9 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 57.6 mg/L
- EC10 or NOEC for freshwater algae:
- 42.9 mg/L
Additional information
The effect of DV6850 on the growth of the unicellular green alga Selenastrum capricornutum was assessed under non-axenic conditions. The study was conducted in accordance with EC Methods C.3 and the OECD Guideline No. 201.
Triplicate algal cultures, with an initial cell density of 1E04/mL, were exposed to aqueous solutions of DV6850 with measured mean concentrations of 4.12, 8.87, 19.8, 42.9 and 85.4 mg/L for 72 hours. Cell numbers were counted daily to monitor growth. At the highest test concentration (85.4 mg/L), levels of growth inhibition based on area under the growth curve and average specific growth rate were 91 and 50%, respectively. The following values were derived from the data:
Area under the growth curve, EbC50 (72 h): 57.6 mg/L (95% confidence limits, 42.9 and 85.4 mg/L)
Average specific growth rate: ErC50 (0 - 72 h): 85.4 mg/L
No observed effect concentration (NOEC): 42.9 mg/L
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