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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
In silico prediction.
Tox Boxes 2.9 is the in house software for the prediction of basic toxicity endpoints in chemicals. Predictions are made analyzing the chemical structure and based upon large validated databases and QSAR models, in combination with expert knowledge of organic chemistry and toxicology.
GLP compliance:
not specified
Test type:
other: in silico prediction

Test material

Constituent 1
Chemical structure
Reference substance name:
1H-indazole-3-carboxylic acid
EC Number:
224-794-5
EC Name:
1H-indazole-3-carboxylic acid
Cas Number:
4498-67-3
Molecular formula:
C8H6N2O2
IUPAC Name:
1H-indazole-3-carboxylic acid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 100 mg/kg bw

Any other information on results incl. tables

Acute toxicity shows values with moderate reliability index.

Applicant's summary and conclusion

Interpretation of results:
other: alert, moderate reliability index
Remarks:
Criteria used for interpretation of results: expert judgment
Conclusions:
Acute toxicity shows values with moderate reliability index.