A mixture of isomers of: mono-(2-tetradecyl)naphthalenes; di-(2-tetradecyl)naphthalenes; tri-(2-tetradecyl)naphthalenes

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1991

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Reliability rating was 1 because study followed OECD 202 (Daphnia sp Acute immobilization) test guidelines and was carried out under GLP

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1991

Report date:

1991

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

MCP 968

IUPAC Name:

MCP 968

Constituent 2

Reference substance name:

A mixture of isomers of: mono-(2-tetradecyl)naphthalenes; di-(2-tetradecyl)naphthalenes; tri-(2-tetradecyl)naphthalenes

EC Number:

410-190-0

EC Name:

A mixture of isomers of: mono-(2-tetradecyl)naphthalenes; di-(2-tetradecyl)naphthalenes; tri-(2-tetradecyl)naphthalenes

Cas Number:

132983-41-6

Molecular formula:

Can vary from C24H36 (mono rxn product) to C52H92 (tri rxn product)

IUPAC Name:

2,3,6-tritetradecylnaphthalene; 2,3-ditetradecylnaphthalene; 2-tetradecylnaphthalene

Details on test material:

- Name of test material (as cited in study report): MCP 968
- Physical state: Liquid
- Analytical purity: 100%

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Remarks on exposure duration:

water soluble fraction (WSF) solutions tested

Test conditions

Hardness:

Hardness of reconstituted freshwater : 207 mg/L as CaCO3

Test temperature:

Test temp: 21-22 C

pH:

pH 7.92 -8.08

Dissolved oxygen:

Dissolved oxygen: 7.5 -7.8 mg/L

Nominal and measured concentrations:

Nominal loadings at 0, 87, 520, 1040, 1994 and 5029 mg/L nominal - generated as water soluble fraction (WSF) solutions

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

EL50

Effect conc.:

> 5 029 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Remarks:

nominal loading

Basis for effect:

other: immobilization

Remarks on result:

other: WSF

Effect concentrations 2

Duration:

48 h

Dose descriptor:

other: NOEL

Effect conc.:

> 5 029 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Remarks:

nominal loading

Basis for effect:

other: immobilization

Remarks on result:

other: WSF

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The test substance did not cause any acute toxicity (i.e., immobilization or abnormal behavior) to Daphnia magna at the five concentrations tested including the highest 5029 mg/L loading exposure. The 48-hr EL50 value was determined to be >5029 mg/L WSF. The NOEL (no observed effect loading) after 48 hr was found to be > 5029 mg/L WSF based on no immobilization at this loading.

Executive summary:

The acute toxicity of the test material, as measured by immobilization to the water flea, Daphnia magna, was evaluated in freshwater. Water soluble fractions solutions of the test material did not produce any acute toxicity to Daphnia even at the highest nominal loadings of 5029 mg/L under the conditions of this study. It was determined that the 48 hr EL50 value was > 5029 mg/L WSF and the NOEL was > 5029 mg/L WSF since no immobilization and no adverse effects were observed. Hence, the test material is not expected to produce acute toxicity at its water solubility level in the WSF in this test.