Registration Dossier
Registration Dossier
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EC number: 239-784-6 | CAS number: 15687-27-1
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- Test set up not in accordance with OECD 208 guideline regarding duration, matrix (no soil), observed endpoints. Only one species tested.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of ibuprofen and perfluorooctanoic acid for risk assessment of mixtures in aquatic and terrestrial environments
- Author:
- González-Naranjo V, Boltes K
- Year:
- 2 014
- Bibliographic source:
- Int J Environ Sci Technol 11:1743-1750; DOI 10.1007/s13762-013-0379-9
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 208 (Terrestrial Plants, Growth Test)
- Deviations:
- yes
- Remarks:
- Test performed with a Phytotoxkit (Microbiotest, Belgium) which is not in accordance with OECD guideline: endpoints observed: seed germination and root elongation after 3 d of exposure. Only one species tested.
- GLP compliance:
- no
Test material
- Reference substance name:
- Sodium 2-(4-isobutylphenyl)propionate
- EC Number:
- 250-477-6
- EC Name:
- Sodium 2-(4-isobutylphenyl)propionate
- Details on test material:
- - Name of test material (as cited in study report): sodium salt of ibuprofen (alpha-methyl-4-[isobutyl]phenylacetid acid)
- Purity: analytical grade substance
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Remarks:
- Stability of test item was not tested on test solutions, but on separately prepared solutions.
Test substrate
- Vehicle:
- no
Test organisms
- Species:
- Sorghum bicolor
- Plant group:
- Monocotyledonae (monocots)
Study design
- Test type:
- seed germination/root elongation toxicity test
- Study type:
- laboratory study
- Substrate type:
- filter paper
- Limit test:
- no
- Total exposure duration:
- 3 d
Results and discussion
Effect concentrations
- Species:
- Sorghum bicolor
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 293.7 other: mg/kg
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- other: seed germination and root elongation
- Remarks on result:
- other: It is not specified if the concentration is based on wet or dry matter
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
