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Key value for chemical safety assessment

Additional information

Short description of key information:
MLA; LumiNova Green did not demonstrate mutagenic potential in this in vitro cell mutation assay, under the experimental conditions described.
Chromosomal aberrations; It is concluded that LumiNova does not induce chromosomal aberration in the presence or absence of metabolic activation under the conditions existing in the present study.
Ames test; It is concluded that, when tested in corn oil, Luminova shows no evidence of mutagenic activity in this bacterial system.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

LumiNova is not classified as genetically toxic.

The three studies undertaken for genetic toxicity, Mouse Lymphoma Assay, Chromosomal Aberrations Study and the Ames Study all returned negative results.

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