Registration Dossier
Registration Dossier
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EC number: 222-883-3 | CAS number: 3648-18-8
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not reported
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The data are taken from an abstract of an internet source with no reported methodology. As a result it is not possible to assess the accuracy of the information. Furthermore, the route of exposure was administered via a non standard route.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 980
Materials and methods
- Principles of method if other than guideline:
- The value is taken from a secondary source citing Robinson (1969). Test guidelines or methods are not mentioned in the literature.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Dioctyltin dilaurate
- EC Number:
- 222-883-3
- EC Name:
- Dioctyltin dilaurate
- Cas Number:
- 3648-18-8
- Molecular formula:
- C40-H80-O4-Sn
- IUPAC Name:
- dioctyltin dilaurate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- female
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LC50
- Effect level:
- 800 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Conclusions:
- The LD50 via intraperitoneal injection is recorded as 800 mg/kg.
- Executive summary:
The test material was reported to have an LD₅₀ 800 mg/kg following administration via intraperitoneal injection to rats. There is no information included in the literature regarding the method used by Robinson (1969). It is not possible to derive a classification from this value as a nonstandard route of exposure was used.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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