Registration Dossier
Registration Dossier
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EC number: 203-459-7 | CAS number: 107-07-3
Repeated dose toxicity: inhalation
Administrative data
- Endpoint:
- repeated dose toxicity: inhalation
- Type of information:
- other: Secondary reference IUCLID4
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
Data source
Reference
- Title:
- No information
- Author:
- Strusevich E.A. et al.
- Year:
- 1 972
- Bibliographic source:
- : Gig. Tr. Prof. Zabol., 11, 42-43,|(1972).|Zitiert in: DIMDI-Toxall, ND: CA/078/053642C, (1973)
Materials and methods
- Principles of method if other than guideline:
- Method: other: no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-chloroethanol
- EC Number:
- 203-459-7
- EC Name:
- 2-chloroethanol
- Cas Number:
- 107-07-3
- Molecular formula:
- C2H5ClO
- IUPAC Name:
- 2-chloroethan-1-ol
- Details on test material:
- IUCLID4 Test substance: as prescribed by 1.1 - 1.4
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Duration of treatment / exposure:
- 4 Monate
- Frequency of treatment:
- kontinuierlich
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0.001; 0.01 mg/l
Basis:
- Control animals:
- other: no data specified
- Details on study design:
- Post-exposure period: ja (keine genaueren Angaben)
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
RS-Freetext:
Die russ. Studie liegt nur als Abstract vor.
In beiden Dosierungen wurde ein Ansteigen des
Blutlecithin- und Blutcholesterolwertes beschrieben, die
auf Stoerungen des Leber-Lipid-Metabolismus hindeuten. Bei
den Tieren der niederen Dosierung konnte 2 Wochen nach
Behandlungsende kein veraenderter Lipidmetabolismus
festgestellt werden. Keine weiteren Angaben liegen vor.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
