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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

Two studies investigated the effects of the test item on immobilisation of Daphnia magna.
In the GLP compliant key study according to OECD 202 guideline, daphnids were exposed under static conditions over 48 hours to five loading levels of 0.500 - 1.00 - 2.00 - 4.00 - 8.00 mg/L. Analytical verification of the test substance showed that the loading rates were within 80 to 120 % of the nominal levels. After 48 hours, the EC50 for immobility was 2.05 mg/L. All validity criteria were met.
In a supporting study, Daphnia magna were exposed to the test item for 24h under static conditions. Daphnids were exposed to control, solvent control, and test item at nominal concentration of 1.0, 1.8, 3.2, 5.8, 10 mg/L for 24 h. The 24h EC50 was 1.4 mg/L. The 24h EC0 based on immobilization was 1 mg/L.   

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2.05 mg/L

Additional information