Registration Dossier
Registration Dossier
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EC number: 231-901-9 | CAS number: 7778-39-4
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
In the US EPA review, a large dataset of aquatic bioaccumulation studies has been investigated; BCF values in this dataset ranged from 0.048 to 1,390. Even if As can be bioconcentrated in aquatic organisms, biomagnification in aquatic food chains does not appear to be significant.
Key value for chemical safety assessment
Additional information
Arsenic acid (AA) is an inorganic compound of arsenic (As) for which a large number of studies addressing the bioaccumulation by various aquatic species are available in the literature. Thus, the study on bioaccumulation of the substance in fish is scientifically unjustified. Further details are provided in the endpoint summary 5.3. A weight of evidence approach is proposed to cover the aquatic bioaccumulation information requirement.
As bioaccumulation depends on various factors including the environmental setting (marine, estuarine, freshwater), the type of aquatic organism, the exposure concentration and duration. In the US EPA review, a large dataset of aquatic bioaccumulation studies has been investigated; BCF values in this dataset ranged from 0.048 to 1,390. Even if As can be bioconcentrated in aquatic organisms, biomagnification in aquatic food chains does not appear to be significant.
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