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EC number: 201-133-9 | CAS number: 78-69-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data available as short summary from a secondary source beeing cited in a peer-reviewed publication
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Acute toxicity studies in rats, mice, rabbits and guinea pigs
- Author:
- Moreno OM,
- Year:
- 1 976
- Bibliographic source:
- Unpublished report to RIFM; Tetrahydrolinalool CAS 78-69-3 RIFM ID 773 FEMA 3060
- Reference Type:
- secondary source
- Title:
- Acute toxicity studies in rats, mice, rabbits and guinea pigs
- Author:
- Moreno OM
- Year:
- 1 976
- Bibliographic source:
- cited in: Opdyke DJM, Food Cosmet. Toxicol., Vol 17, p. 909, 1979
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- A dermal LD50 study was conducted in which 5 g/kg of the test material was applied to the skin of 10 rats. The animals were observed for mortality and/or systemic effects for 14 days. No further details were provided.
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- 3,7-dimethyloctan-3-ol
- EC Number:
- 201-133-9
- EC Name:
- 3,7-dimethyloctan-3-ol
- Cas Number:
- 78-69-3
- Molecular formula:
- C10H22O
- IUPAC Name:
- 3,7-dimethyloctan-3-ol
- Details on test material:
- - Name of test material (as cited in study report): Tetrahydrolinalool = THL
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Doses:
- no data
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
Applicant's summary and conclusion
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