Registration Dossier
Registration Dossier
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EC number: 228-601-5 | CAS number: 6303-21-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Three genetic toxicity tests were performed under GLP conditions on Sodium hypophosphite, the parent compound of the phosphinic acid. All the 3 tests gave negative results:
- reverse mutation in bacteria (OECD guideline 471 and the EU Method B13/14)
- chromosome aberrations in cultured human lymphocytes (OECD guideline 473 and the EU Method B.10)
- mutations in L5178Y TK+/- mouse lymphoma (OECD guideline 476 and EU method B.17).
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
According to regulation 67-548 EEC and CLP regulation(EC) N° 1272/2008, Phosphinic acid is not classified as mutagenic.
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