Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 295-298-4 | CAS number: 91995-38-9 A complex combination of hydrocarbons obtained as first runnings from the depentanizer column before hydrotreatment of the aromatic charges. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C4 through C6, predominantly pentanes and pentenes, and boiling in the range of approximately 25°C to 40°C (77°F to 104°F).
Unleaded gasoline samples API 91-01 and API PS-6 were both administered via semi-occlusive patch for four hours to two groups of 6 New Zealand White rabbits (one group per test material) to assess dermal irritation. Dermal responses were evaluated at 1, 24, 48, and 72h post-dosing and on Days 7, 10, and 14 according to the Draize method of scoring. Animals administered API 91-01 exhibited moderate to severe erythema (grade 3) at the 24h, 48h and 72h observation point. The erythema was fully reversible within 14 days. In the same group, maximum edema was noted in the 1st hour of observation and fluctuated with severity from slight (grade 2, 24 h) to very slight and no edema (grade 0/1, day 7); all animals were clear of edema by Day 14. Animals administered API PS-6 exhibited moderate erythema (grade 2) at the 24h, 48h, and 72 h observation point. The erythema was fullly reversible within 14 days. Maximum edema was observed 1h after removal of the patch and irritation due to edema subsided and was clear by Day 14 of the observation period. The mean erythema and edema scores for API 91-01 were 2.56 and 1.89, respectively. The mean erythema and edema score for API PS-6 were 2.39 and 1.39, respectively. This finding warrants classification of API 91-01 and API PS-6 as irritating under Regulation (EC) 1272/2008 on classification, labeling, and packaging of substances and mixtures (CLP) and as an R38 skin irritant under the Directive 67/518/EEC for dangerous substances and Directive 1999/45/EC for preparations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again