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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Skin Irritatin / Corrosion:
Dicerium tricarbonate is not a dermal irritant.
Eye Irritation / Corrosion:
Dicerium tricarbonate is slightly irritant to the eye but not classified according to EU criteria.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Skin and eye irritation were tested in vivo by Lambert et al, 1990. The study was evaluated as reliable 2 according to the Klimish cotation.

In this primary dermal irritation study, 6 New Zealand Albino rabbits were dermally exposed to 0.5 g of dicerium tricarbonate (purity unknown) for 24 hours to ca. 2.5 cm² of one intact and one abraded skin site. Test sites were covered with an occlusive dressing for 24 hours. Animals then were observed for 3 days. Irritation was scored by the method of Draize. No relevant irritation was observed and the study concluded that Dicerium Tricarbonate doens't show any dermal irritation properties.

For the eye irritation study part, 0.1 g of dicerium tricarbonate (purity unknown) was instilled into the left eye of New Zealand Albino rabbits (6 animals). 3 treated eyes were rinsed after 30 seconds. Animals then were observed for 3 days. Irritation was scored by the method of Draize, showing slightly irritations but no classification should be proposed according to the criteria of the annex VI of the directive 67/548/CEE.

Justification for classification or non-classification

Skin irritation: As dicerium tricarbonate did not induce any skin irritation effects, it does not need to be classified according toclassification criteria of Annex VI Directive 67/548/EEC or UN/EU GHS classification system.

 

Eye irritation: Dicerium tricarbonate is slightly irritant to the eye, but does not need to be classified according toclassification criteria of Annex VI Directive 67/548/EEC or UN/EU GHS classification system.