Registration Dossier
Registration Dossier
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EC number: 200-467-2 | CAS number: 60-29-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 = 2560 mg/L, 96h, flow-through, fathead minnow (Geiger)
LC50 = 2138 mg/L, 14 days, semi-static, guppy (Könemann)
LC50 = 2840 mg/L, 48h, static, golden orfe (Juhnke)
LC50 > 10000 mg/L, 96h, static, bluegill sunfish (Dawson)
LC50 > 10000 mg/L, 96h, static, tidewater silverside, saltwater (Dawson)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2 138 mg/L
Additional information
The tests by Juhnke (1978) were following an early guideline, however, the testing period was only 48h. Losses by volatilisation were possible. The results reported by Könemann (1981) are considered to be more reliable considering maintenance of the test substance concentration (the test solution was replaced daily and the aquaria glass covered) and the extended test period (14d). The guideline flow-through study by Geiger (1986) is considered to be the most reliable result, however, the most conservative value (Könemann) is selected as the key parameter to be taken forward to the risk assessment.
The studies by Dawson (1976) are considered to be unreliable due to probable loss of test substance through volatilisation.
The available data is considered to be adequate and conclusive for classification and labelling, and risk assessment purposes, based on the weight-of-evidence.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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