Registration Dossier
Registration Dossier
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EC number: 215-146-2 | CAS number: 1306-19-0
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- short-term repeated dose toxicity: dermal
- Data waiving:
- exposure considerations
- Justification for data waiving:
- other:
- Justification for type of information:
- No studies were located regarding chronic effects after dermal exposure to cadmium metal or cadmium compounds. However, repeated dose toxicity via the dermal route is not expected to be significant as uptake of soluble and less-soluble cadmium compounds applied onto the skin of animals appears to be low (<1%) (see Section 5.1.1). Also in view of the risk reduction measures which need to be taken as a result of the carcinogenicity of cadmium metal and some of the cadmium compounds, dermal toxicity is not likely to pose an issue for human health.
Data source
Materials and methods
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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